| Gene Symbol |
LIN9
|
| Entrez Gene |
286826
|
| Alt Symbol |
BARA, BARPsv, Lin-9, TGS, TGS1, TGS2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lin-9 DREAM MuvB core complex component
|
| Other Description |
TUDOR gene similar protein|beta subunit-associated regulator of apoptosis|lin-9 homolog|pRB-associated protein|protein lin-9 homolog|rb related pathway actor|type I interferon receptor beta chain-associated protein
|
| Swissprots |
Q5U7E1 Q7Z3J1 Q6PI55 Q5U5L8 Q6ZTV4 Q5TKA1
|
| Accessions |
EAW69780 EAW69781 EAW69782 Q5TKA1 AF190323 AAQ13710 AF190324 AAQ13711 AK125690 AK126177 BAC86475 AK308823 AY166858 AAN87840 AY166859 AAN87841 AY786184 AAV41873 BC043444 AAH43444 BC045625 AAH45625 BC065302 AAH65302 BX537869 CAD97871 XM_005273102 XP_005273159 XM_006711766 XP_006711829 XM_006711767 XP_006711830 XM_011544173 XP_011542475 XR_949138 NM_001270409 NP_001257338 NM_001270410 NP_001257339 NM_173083 NP_775106
|
| Function |
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. {ECO:0000269|PubMed:15538385, ECO:0000269|PubMed:16730350}.
|
| Subcellular Location |
Nucleus, nucleoplasm {ECO:0000269|PubMed:15538385, ECO:0000269|PubMed:16730350}. Note=Found in perinucleolar structures. Associated with chromatin.
|
| Tissue Specificity |
Expressed in thymus and testis. {ECO:0000269|PubMed:15538385}.
|
![Western Blot: LIN9 Overexpression Lysate (Adult Normal) [NBP2-05151] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LIN9.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/24202_LIN9%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-05151-img0001.jpg)