| Gene Symbol |
CATIP
|
| Entrez Gene |
375307
|
| Alt Symbol |
C2orf62
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ciliogenesis associated TTC17 interacting protein
|
| Other Description |
ciliogenesis-associated TTC17-interacting protein
|
| Swissprots |
Q7Z7H3
|
| Accessions |
EAW70610 Q7Z7H3 AK098178 BC052750 AAH52750 HQ448628 ADQ33106 XM_005246539 XP_005246596 XM_005246541 XP_005246598 XM_011511147 XP_011509449 XM_011511148 XP_011509450 XM_011511149 XP_011509451 XM_011511150 XP_011509452 NM_198559 NP_940961
|
| Function |
Plays a role in primary ciliogenesis by modulating actin polymerization. {ECO:0000269|PubMed:24475127}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:24475127}. Cytoplasm {ECO:0000269|PubMed:24475127}. Cell membrane {ECO:0000269|PubMed:24475127}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24475127}. Note=Colocalized with TTC17 at F- actin rich zones and at dynamic plasma membrane protrusions.
|
| Tissue Specificity |
Strongly expressed in round and elongating spermatids, weakly in pachytene spermatocytes. Expressed in Leydig cells (at protein level). Expressed in testis, placenta, prostate and lung, and moderately in ovary and brain. {ECO:0000269|PubMed:24475127}.
|
![Western Blot: C2orf62 Overexpression Lysate (Adult Normal) [NBL1-08424] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C2orf62.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1168_C2orf62%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08424-img0002.jpg)