Gene Symbol | CATIP |
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Entrez Gene | 375307 |
Alt Symbol | C2orf62 |
Species | Human |
Gene Type | protein-coding |
Description | ciliogenesis associated TTC17 interacting protein |
Other Description | ciliogenesis-associated TTC17-interacting protein |
Swissprots | Q7Z7H3 |
Accessions | EAW70610 Q7Z7H3 AK098178 BC052750 AAH52750 HQ448628 ADQ33106 XM_005246539 XP_005246596 XM_005246541 XP_005246598 XM_011511147 XP_011509449 XM_011511148 XP_011509450 XM_011511149 XP_011509451 XM_011511150 XP_011509452 NM_198559 NP_940961 |
Function | Plays a role in primary ciliogenesis by modulating actin polymerization. {ECO:0000269|PubMed:24475127}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:24475127}. Cytoplasm {ECO:0000269|PubMed:24475127}. Cell membrane {ECO:0000269|PubMed:24475127}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24475127}. Note=Colocalized with TTC17 at F- actin rich zones and at dynamic plasma membrane protrusions. |
Tissue Specificity | Strongly expressed in round and elongating spermatids, weakly in pachytene spermatocytes. Expressed in Leydig cells (at protein level). Expressed in testis, placenta, prostate and lung, and moderately in ovary and brain. {ECO:0000269|PubMed:24475127}. |
C2orf62 CRISPR/Cas9 KO Plasmid (h) - sc-415710 from Santa Cruz Biotechnology
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C2orf62 HDR Plasmid (h) - sc-415710-HDR from Santa Cruz Biotechnology
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C2orf62 Double Nickase Plasmid (h) - sc-415710-NIC from Santa Cruz Biotechnology
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C2orf62 Double Nickase Plasmid (h2) - sc-415710-NIC-2 from Santa Cruz Biotechnology
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C2orf62 CRISPR Activation Plasmid (h) - sc-415710-ACT from Santa Cruz Biotechnology
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C2orf62 CRISPR Activation Plasmid (h2) - sc-415710-ACT-2 from Santa Cruz Biotechnology
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C2orf62 Lentiviral Activation Particles (h) - sc-415710-LAC from Santa Cruz Biotechnology
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C2orf62 Lentiviral Activation Particles (h2) - sc-415710-LAC-2 from Santa Cruz Biotechnology
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C2orf62 siRNA (h) - sc-95042 from Santa Cruz Biotechnology
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C2orf62 shRNA Plasmid (h) - sc-95042-SH from Santa Cruz Biotechnology
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C2orf62 shRNA (h) Lentiviral Particles - sc-95042-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU010291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4844 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4844 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11980 from Sigma-Aldrich
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CATIP siRNA (Human) - CRJ7661 from Cohesion Biosciences
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C2orf62 RNAi - H00375307-R01 from Novus Biologicals
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CATIP - MBS8237365 from MyBioSource
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shRNA set against Human C2orf62 (NM_198559.1) - SHH251433 from Creative biogene
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Human CATIP siRNA - orb278162 from Biorbyt
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CATIP shRNA Plasmid (Human) - CHJ7661 from Cohesion Biosciences
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C2ORF62 miRNA 3'UTR clone - MiUTR1H-06286 from Creative biogene
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