GRIA4

Gene Symbol	GRIA4
Entrez Gene	2893
Alt Symbol	GLUR4, GLUR4C, GLURD, GluA4
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, AMPA 4
Other Description	AMPA-selective glutamate receptor 4|gluR-4|gluR-D|glutamate receptor 4|glutamate receptor, ionotrophic, AMPA 4
Swissprots	P48058 Q86XE8
Accessions	EAW67066 EAW67067 EAW67068 EAW67069 P48058 AB115416 BAD23796 AB209092 BAD92329 AK311193 BC015199 BC035610 BC045546 AAH45546 BC114549 AAI14550 BC142654 AAI42655 BC146816 AAI46817 BC150209 AAI50210 BC167786 AAI67786 BM675457 BM723114 DA077870 DA391203 DB298333 DB305322 DB473702 DB548729 FJ947075 ACR45952 FJ947076 ACR45953 JN547407 AEQ93811 U16129 AAA95962 XM_005271518 XP_005271575 XM_006718823 XP_006718886 XM_011542775 XP_011541077 XM_011542776 XP_011541078 XM_011542777 XP_011541079 XR_947825 NM_000829 NP_000820 NM_001077243 NP_001070711 NM_001077244 NP_001070712 NM_001112812 NP_001106283 NR_046356
Function	Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. {ECO:0000269|PubMed:21172611}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression. {ECO:0000250}.
Top Pathways	Glutamatergic synapse, Dopaminergic synapse, Amphetamine addiction, Nicotine addiction, Retrograde endocannabinoid signaling

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AMPA Receptor (GluR 4) (D41A11) XP ® Rabbit mAb - 8070 from Cell Signaling Technology Prices $109.00, $277.00 Sizes 20 µl (2 western blots), 100 µl (10 western blots) Host Rabbit Clonality Monoclonal Clone D41A11

AMPA Receptor (GluR 4) (D19G9) Rabbit mAb - 8010 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Monoclonal Clone D19G9

AMPA Receptor (GluR 4) (Arg860) Antibody - 3825 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

AMPA Receptor (GluR 4) (Ala60) Antibody - 3824 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

GluR-4 (F-9) - sc-271894 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

GluR-4 (C-20) - sc-7614 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GluR-4 (H-20) - sc-31394 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

GluR-4 (H-45) - sc-134504 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-Ionotropic Glutamate receptor 4 (phospho S862) antibody - ab61054 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Ionotropic Glutamate receptor 4 antibody - ab87610 from Abcam Host Rabbit Clonality Polyclonal

Anti-Ionotropic Glutamate receptor 4 antibody - ab171423 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-Ionotropic Glutamate receptor 4 antibody - ab61171 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Ionotropic Glutamate receptor 4 antibody [EPR2511(2)] - ab119995 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR2511(2)

Anti-Ionotropic Glutamate receptor 4 antibody [EPR2512(2)] - ab109431 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR2512(2)

Anti-GRIA4 / GLUR4 Antibody (aa889-902) - LS-C15373 from LifeSpan Bioscience Prices $515.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa828-877) - LS-C117902 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa259-287, AP) - LS-C258042 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa259-287, APC) - LS-C258043 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa259-287, Biotin) - LS-C258044 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa259-287, Azide-free, HRP) - LS-C258046 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa259-287, FITC) - LS-C258045 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa259-287, PE) - LS-C258047 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa296-325, AP) - LS-C258048 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa296-325, APC) - LS-C258049 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-GRIA4 / GLUR4 Antibody (aa296-325, Biotin) - LS-C258050 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Search more