GRIA4

Gene Symbol	GRIA4
Entrez Gene	2893
Alt Symbol	GLUR4, GLUR4C, GLURD, GluA4
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, ionotropic, AMPA 4
Other Description	AMPA-selective glutamate receptor 4|gluR-4|gluR-D|glutamate receptor 4|glutamate receptor, ionotrophic, AMPA 4
Swissprots	P48058 Q86XE8
Accessions	EAW67066 EAW67067 EAW67068 EAW67069 P48058 AB115416 BAD23796 AB209092 BAD92329 AK311193 BC015199 BC035610 BC045546 AAH45546 BC114549 AAI14550 BC142654 AAI42655 BC146816 AAI46817 BC150209 AAI50210 BC167786 AAI67786 BM675457 BM723114 DA077870 DA391203 DB298333 DB305322 DB473702 DB548729 FJ947075 ACR45952 FJ947076 ACR45953 JN547407 AEQ93811 U16129 AAA95962 XM_005271518 XP_005271575 XM_006718823 XP_006718886 XM_011542775 XP_011541077 XM_011542776 XP_011541078 XM_011542777 XP_011541079 XR_947825 NM_000829 NP_000820 NM_001077243 NP_001070711 NM_001077244 NP_001070712 NM_001112812 NP_001106283 NR_046356
Function	Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. {ECO:0000269|PubMed:21172611}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression. {ECO:0000250}.
Top Pathways	Glutamatergic synapse, Dopaminergic synapse, Amphetamine addiction, Nicotine addiction, Retrograde endocannabinoid signaling

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Ionotropic Glutamate receptor 4 full length protein - ab152441 from Abcam Category Protein Source Wheat germ Species Human

GRIA4 / GLUR4 Antibody Blocking Peptide - LS-E442 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRIA4 / GLUR4 Antibody Blocking Peptide - LS-E2057 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GRIA4 / GLUR4 Antibody Blocking Peptide - LS-E26704 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Glutamate Receptor 4 Protein - H00002893-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GRIA4-Antibody-Center-Blocking-peptide - BP10724c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRIA4-Antibody-Center-Blocking-peptide - BP12941c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GluR4 blocking peptide - GTX88589-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

GLUR4 (phospho-Ser862) Blocking Peptide - abx062696 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken, Monkey, Zebrafish

Ionotropic Glutamate Receptor 4 Peptide - AC21-1543-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Glutamate receptor 4 / GLUR4 - H00002893-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Glutamate receptor 4 / GLUR4 - H00002893-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GRIA4 Peptide - 46-724P from ProSci Category Peptide Species Human

GRIA4 fusion protein - ag19933 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GRIA4 fusion protein - Ag19949 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human GRIA4 - GRIA4-216H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) - RPE804Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) - RPE804Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) - RPE804Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

GLUR4 (pS862) Blocking Peptide - CBP1502 from Cohesion Biosciences Category Peptide Prices $150.00, $450.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Chicken, Monkey, Zebrafish

GluR4 (K858) Peptide - BS1649P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

p-GluR4 (S862) Peptide - BS4690P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) - RPE804Hu01 from Cloud-clone Category Protein Source E.coli Species Human

GRIA4, Peptide - MBS425250 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine

GLUR4 Blocking Peptide - abx061623 from Abbexa Category Peptide

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