| Gene Symbol |
UBE2Q1
|
| Entrez Gene |
55585
|
| Alt Symbol |
GTAP, NICE-5, PRO3094, UBE2Q
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin-conjugating enzyme E2Q family member 1
|
| Other Description |
galactosyl transferase-associated protein|protein NICE-5|ubiquitin carrier protein Q1|ubiquitin-conjugating enzyme E2 Q1|ubiquitin-conjugating enzyme E2Q (putative) 1|ubiquitin-protein ligase Q1
|
| Swissprots |
Q96MV4 Q6IS04 Q7Z7E8 Q5I0X2 B4DF92 Q3B841 Q9BVX5 Q29SN7 Q9UGL6 Q6P7P2
|
| Accessions |
EAW53193 Q7Z7E8 AF116721 AAF71141 AJ243666 CAB65097 AK056388 BAB71173 AK293986 BAG57353 AY112698 AAM60814 AY948200 AAY23342 BC000848 AAH00848 BC009286 BC015316 AAH15316 BC061583 AAH61583 BC070158 AAH70158 BC087836 AAH87836 BC107057 AAI07058 BC148185 AAI48186 BC172317 AAI72317 BQ278712 CA391436 CR457219 CAG33500 NM_017582 NP_060052
|
| Function |
Catalyzes the covalent attachment of ubiquitin to other proteins (Potential). May be involved in hormonal homeostasis in females (By similarity). Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity). {ECO:0000250|UniProtKB:Q7TSS2, ECO:0000255|PROSITE- ProRule:PRU00388}.
|
| Subcellular Location |
Nucleus {ECO:0000250|UniProtKB:Q7TSS2}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q7TSS2}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q7TSS2}.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:11230159}.
|
| Top Pathways |
Ubiquitin mediated proteolysis
|
![Western Blot: UBE2Q1 Overexpression Lysate (Adult Normal) [NBP2-06958] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UBE2Q1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1629_UBE2Q1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06958-img0001.jpg)