Gene Symbol | UBE2Q1 |
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Entrez Gene | 55585 |
Alt Symbol | GTAP, NICE-5, PRO3094, UBE2Q |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2Q family member 1 |
Other Description | galactosyl transferase-associated protein|protein NICE-5|ubiquitin carrier protein Q1|ubiquitin-conjugating enzyme E2 Q1|ubiquitin-conjugating enzyme E2Q (putative) 1|ubiquitin-protein ligase Q1 |
Swissprots | Q96MV4 Q6IS04 Q7Z7E8 Q5I0X2 B4DF92 Q3B841 Q9BVX5 Q29SN7 Q9UGL6 Q6P7P2 |
Accessions | EAW53193 Q7Z7E8 AF116721 AAF71141 AJ243666 CAB65097 AK056388 BAB71173 AK293986 BAG57353 AY112698 AAM60814 AY948200 AAY23342 BC000848 AAH00848 BC009286 BC015316 AAH15316 BC061583 AAH61583 BC070158 AAH70158 BC087836 AAH87836 BC107057 AAI07058 BC148185 AAI48186 BC172317 AAI72317 BQ278712 CA391436 CR457219 CAG33500 NM_017582 NP_060052 |
Function | Catalyzes the covalent attachment of ubiquitin to other proteins (Potential). May be involved in hormonal homeostasis in females (By similarity). Involved in regulation of B4GALT1 cell surface expression, B4GALT1-mediated cell adhesion to laminin and embryoid body formation (By similarity). {ECO:0000250|UniProtKB:Q7TSS2, ECO:0000255|PROSITE- ProRule:PRU00388}. |
Subcellular Location | Nucleus {ECO:0000250|UniProtKB:Q7TSS2}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q7TSS2}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q7TSS2}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11230159}. |
Top Pathways | Ubiquitin mediated proteolysis |
UBE2Q1 CRISPR/Cas9 KO Plasmid (h) - sc-412549 from Santa Cruz Biotechnology
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UBE2Q1 HDR Plasmid (h) - sc-412549-HDR from Santa Cruz Biotechnology
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UBE2Q1 Double Nickase Plasmid (h) - sc-412549-NIC from Santa Cruz Biotechnology
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UBE2Q1 Double Nickase Plasmid (h2) - sc-412549-NIC-2 from Santa Cruz Biotechnology
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UBE2Q1 CRISPR Activation Plasmid (h) - sc-412549-ACT from Santa Cruz Biotechnology
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UBE2Q1 CRISPR Activation Plasmid (h2) - sc-412549-ACT-2 from Santa Cruz Biotechnology
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UBE2Q1 Lentiviral Activation Particles (h) - sc-412549-LAC from Santa Cruz Biotechnology
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UBE2Q1 Lentiviral Activation Particles (h2) - sc-412549-LAC-2 from Santa Cruz Biotechnology
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UBE2Q1 siRNA (h) - sc-76790 from Santa Cruz Biotechnology
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UBE2Q1 shRNA Plasmid (h) - sc-76790-SH from Santa Cruz Biotechnology
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UBE2Q1 shRNA (h) Lentiviral Particles - sc-76790-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU055921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22378 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22378 from Sigma-Aldrich
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UBE2Q1 siRNA (Human) - CRJ0753 from Cohesion Biosciences
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UBE2Q1 - MBS8203860 from MyBioSource
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shRNA set against Human UBE2Q1 (NM_017582.6) - SHH439120 from Creative biogene
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Human UBE2Q1 siRNA - orb271254 from Biorbyt
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UBE2Q1 shRNA Plasmid (Human) - CHJ0753 from Cohesion Biosciences
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UBE2Q1 miRNA 3'UTR clone - MiUTR1H-10956 from Creative biogene
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