Gene Symbol | ELF1 |
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Entrez Gene | 1997 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | E74-like factor 1 (ets domain transcription factor) |
Other Description | ETS-related transcription factor Elf-1 |
Swissprots | Q9UDE1 B4E2I5 E9PDQ9 Q8N6F6 P32519 |
Accessions | CCQ43123 EAX08640 EAX08641 P32519 AK095466 BAG53061 AK304289 BAG65147 BC010575 BC030507 AAH30507 BQ722965 BX640798 CAE45881 DC418141 DQ891709 ABM82635 DQ894886 ABM85812 M82882 XM_005266276 XP_005266333 XM_005266277 XP_005266334 XM_011534950 XP_011533252 XM_011534951 XP_011533253 XM_011534952 XP_011533254 NM_001145353 NP_001138825 NM_172373 NP_758961 |
Function | Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. {ECO:0000269|PubMed:8756667}. |
Subcellular Location | Nucleus. |
Tissue Specificity | In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis. {ECO:0000269|PubMed:8756667, ECO:0000269|PubMed:9524226}. |
ELF1 293T Cell Transient Overexpression Lysate(Denatured) - H00001997-T01 from Acris Antibodies
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E74 like factor 1 Overexpression Lysate (Denatured) - H00001997-T01 from Novus Biologicals
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Elf-1 (h): 293T Lysate - sc-114811 from Santa Cruz Biotechnology
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Elf-1 (h2): 293T Lysate - sc-176605 from Santa Cruz Biotechnology
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Elf-1 (h3): 293T Lysate - sc-159174 from Santa Cruz Biotechnology
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Panoply™ Human ELF1 Knockdown Stable Cell Line - CSC-DC004853 from Creative biogene
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