Gene Symbol | ELF1 |
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Entrez Gene | 1997 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | E74-like factor 1 (ets domain transcription factor) |
Other Description | ETS-related transcription factor Elf-1 |
Swissprots | Q9UDE1 B4E2I5 E9PDQ9 Q8N6F6 P32519 |
Accessions | CCQ43123 EAX08640 EAX08641 P32519 AK095466 BAG53061 AK304289 BAG65147 BC010575 BC030507 AAH30507 BQ722965 BX640798 CAE45881 DC418141 DQ891709 ABM82635 DQ894886 ABM85812 M82882 XM_005266276 XP_005266333 XM_005266277 XP_005266334 XM_011534950 XP_011533252 XM_011534951 XP_011533253 XM_011534952 XP_011533254 NM_001145353 NP_001138825 NM_172373 NP_758961 |
Function | Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. {ECO:0000269|PubMed:8756667}. |
Subcellular Location | Nucleus. |
Tissue Specificity | In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis. {ECO:0000269|PubMed:8756667, ECO:0000269|PubMed:9524226}. |
Elf-1 CRISPR/Cas9 KO Plasmid (h) - sc-416289 from Santa Cruz Biotechnology
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Elf-1 HDR Plasmid (h) - sc-416289-HDR from Santa Cruz Biotechnology
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Elf-1 Double Nickase Plasmid (h) - sc-416289-NIC from Santa Cruz Biotechnology
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Elf-1 Double Nickase Plasmid (h2) - sc-416289-NIC-2 from Santa Cruz Biotechnology
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Elf-1 CRISPR Activation Plasmid (h) - sc-416289-ACT from Santa Cruz Biotechnology
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Elf-1 CRISPR Activation Plasmid (h2) - sc-416289-ACT-2 from Santa Cruz Biotechnology
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Elf-1 Lentiviral Activation Particles (h) - sc-416289-LAC from Santa Cruz Biotechnology
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Elf-1 Lentiviral Activation Particles (h2) - sc-416289-LAC-2 from Santa Cruz Biotechnology
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Elf-1 siRNA (h) - sc-37837 from Santa Cruz Biotechnology
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Elf-1 shRNA Plasmid (h) - sc-37837-SH from Santa Cruz Biotechnology
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Elf-1 shRNA (h) Lentiviral Particles - sc-37837-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU000141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7799 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7799 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09670 from Sigma-Aldrich
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ELF1 siRNA (Human) - CRH1381 from Cohesion Biosciences
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ELF1 - MBS8217656 from MyBioSource
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Human ELF1 siRNA - orb261883 from Biorbyt
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ELF1 shRNA Plasmid (Human) - CHH1381 from Cohesion Biosciences
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ELF1 miRNA 3'UTR clone - MiUTR1H-03189 from Creative biogene
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ELF1 miRNA 3'UTR clone - MiUTR3H-02255 from Creative biogene
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