| Gene Symbol |
NMRK1
|
| Entrez Gene |
54981
|
| Alt Symbol |
C9orf95, NRK1, bA235O14.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nicotinamide riboside kinase 1
|
| Other Description |
NRK 1|RNK 1|nicotinic acid riboside kinase 1|nmR-K 1|ribosylnicotinamide kinase 1|ribosylnicotinic acid kinase 1
|
| Swissprots |
Q8N430 Q5W124 Q9NWW6
|
| Accessions |
CAM12700 EAW62568 EAW62569 Q9NWW6 AK000566 BAA91259 AK023413 BAG51188 AK097144 BAG53425 AY611480 AAT11928 BC001366 AAH01366 BC026243 BC036804 AAH36804 CB135264 XM_006717162 XP_006717225 XM_006717163 XP_006717226 XM_011518817 XP_011517119 XM_011518818 XP_011517120 XM_011518819 XP_011517121 NM_001127603 NP_001121075 NM_017881 NP_060351 NR_023352
|
| Function |
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3- deazaguanosine. {ECO:0000269|PubMed:15137942}.
|
| Top Pathways |
Nicotinate and nicotinamide metabolism
|
![Western Blot: NRK1 Overexpression Lysate (Adult Normal) [NBL1-08607] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NRK1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3875_NRK1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08607-img0002.jpg)