Gene Symbol | NMRK1 |
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Entrez Gene | 54981 |
Alt Symbol | C9orf95, NRK1, bA235O14.2 |
Species | Human |
Gene Type | protein-coding |
Description | nicotinamide riboside kinase 1 |
Other Description | NRK 1|RNK 1|nicotinic acid riboside kinase 1|nmR-K 1|ribosylnicotinamide kinase 1|ribosylnicotinic acid kinase 1 |
Swissprots | Q8N430 Q5W124 Q9NWW6 |
Accessions | CAM12700 EAW62568 EAW62569 Q9NWW6 AK000566 BAA91259 AK023413 BAG51188 AK097144 BAG53425 AY611480 AAT11928 BC001366 AAH01366 BC026243 BC036804 AAH36804 CB135264 XM_006717162 XP_006717225 XM_006717163 XP_006717226 XM_011518817 XP_011517119 XM_011518818 XP_011517120 XM_011518819 XP_011517121 NM_001127603 NP_001121075 NM_017881 NP_060351 NR_023352 |
Function | Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3- deazaguanosine. {ECO:0000269|PubMed:15137942}. |
Top Pathways | Nicotinate and nicotinamide metabolism |
NRK1 CRISPR/Cas9 KO Plasmid (h) - sc-407802 from Santa Cruz Biotechnology
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NRK1 HDR Plasmid (h) - sc-407802-HDR from Santa Cruz Biotechnology
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NRK1 Double Nickase Plasmid (h) - sc-407802-NIC from Santa Cruz Biotechnology
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NRK1 Double Nickase Plasmid (h2) - sc-407802-NIC-2 from Santa Cruz Biotechnology
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NRK1 CRISPR Activation Plasmid (h) - sc-407802-ACT from Santa Cruz Biotechnology
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NRK1 CRISPR Activation Plasmid (h2) - sc-407802-ACT-2 from Santa Cruz Biotechnology
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NRK1 Lentiviral Activation Particles (h) - sc-407802-LAC from Santa Cruz Biotechnology
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NRK1 Lentiviral Activation Particles (h2) - sc-407802-LAC-2 from Santa Cruz Biotechnology
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NRK1 siRNA (h) - sc-92471 from Santa Cruz Biotechnology
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NRK1 shRNA Plasmid (h) - sc-92471-SH from Santa Cruz Biotechnology
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NRK1 shRNA (h) Lentiviral Particles - sc-92471-V from Santa Cruz Biotechnology
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NRK1 RNAi - H00054981-R02 from Novus Biologicals
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MISSION® esiRNA - EHU097861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5237 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5237 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02695 from Sigma-Aldrich
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NMRK1 siRNA (Human) - CRJ0379 from Cohesion Biosciences
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shRNA set against Human C9orf95 (NM_017881.2) - SHH253025 from Creative biogene
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NMRK1 shRNA Plasmid (Human) - CHJ0379 from Cohesion Biosciences
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NMRK1 miRNA 3'UTR clone - MiUTR3H-10158 from Creative biogene
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NMRK1 miRNA 3'UTR clone - MiUTR3H-10159 from Creative biogene
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