| Gene Symbol |
PIP5KL1
|
| Entrez Gene |
138429
|
| Alt Symbol |
PIPKH, bA203J24.5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylinositol-4-phosphate 5-kinase-like 1
|
| Other Description |
PI(4)P 5-kinase-like protein 1|phosphatidylinositol 4-phosphate 5-kinase-like protein 1|phosphatidylinositol phosphate kinase homolog|phosphatidylinositol-4-phosphate 5-kinase-like protein 1|ptdIns(4)P-5-kinase-like protein 1
|
| Swissprots |
Q8IVS3 Q5T9C9
|
| Accessions |
EAW87722 EAW87723 EAW87724 EAW87725 EAW87726 EAW87727 EAW87728 Q5T9C9 BC042184 AAH42184 BE881330 HQ448498 ADQ32978 NM_173492 NP_775763 NM_001135219 NP_001128691
|
| Function |
May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures. {ECO:0000250}.
|
| Top Pathways |
Endocytosis, Inositol phosphate metabolism
|
![Western Blot: PIP5KL1 Overexpression Lysate (Adult Normal) [NBL1-14437] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PIP5KL1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4486_PIP5KL1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14437-img0002.jpg)