Gene Symbol | PIP5KL1 |
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Entrez Gene | 138429 |
Alt Symbol | PIPKH, bA203J24.5 |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol-4-phosphate 5-kinase-like 1 |
Other Description | PI(4)P 5-kinase-like protein 1|phosphatidylinositol 4-phosphate 5-kinase-like protein 1|phosphatidylinositol phosphate kinase homolog|phosphatidylinositol-4-phosphate 5-kinase-like protein 1|ptdIns(4)P-5-kinase-like protein 1 |
Swissprots | Q8IVS3 Q5T9C9 |
Accessions | EAW87722 EAW87723 EAW87724 EAW87725 EAW87726 EAW87727 EAW87728 Q5T9C9 BC042184 AAH42184 BE881330 HQ448498 ADQ32978 NM_173492 NP_775763 NM_001135219 NP_001128691 |
Function | May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3. {ECO:0000250}. |
Subcellular Location | Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures. {ECO:0000250}. |
Top Pathways | Endocytosis, Inositol phosphate metabolism |
PIPKH CRISPR/Cas9 KO Plasmid (h) - sc-414451 from Santa Cruz Biotechnology
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PIPKH HDR Plasmid (h) - sc-414451-HDR from Santa Cruz Biotechnology
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PIPKH Double Nickase Plasmid (h) - sc-414451-NIC from Santa Cruz Biotechnology
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PIPKH Double Nickase Plasmid (h2) - sc-414451-NIC-2 from Santa Cruz Biotechnology
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PIPKH CRISPR Activation Plasmid (h) - sc-414451-ACT from Santa Cruz Biotechnology
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PIPKH CRISPR Activation Plasmid (h2) - sc-414451-ACT-2 from Santa Cruz Biotechnology
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PIPKH Lentiviral Activation Particles (h) - sc-414451-LAC from Santa Cruz Biotechnology
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PIPKH Lentiviral Activation Particles (h2) - sc-414451-LAC-2 from Santa Cruz Biotechnology
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PIPKH siRNA (h) - sc-92473 from Santa Cruz Biotechnology
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PIPKH shRNA Plasmid (h) - sc-92473-SH from Santa Cruz Biotechnology
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PIPKH shRNA (h) Lentiviral Particles - sc-92473-V from Santa Cruz Biotechnology
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PIP5KL1 RNAi - H00138429-R02 from Novus Biologicals
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MISSION® esiRNA - EHU120201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16830 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16830 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02848 from Sigma-Aldrich
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PIP5KL1 siRNA (Human) - CRJ5225 from Cohesion Biosciences
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shRNA set against Human PIP5KL1 (NM_173492.1) - SHH376064 from Creative biogene
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Human PIP5KL1 siRNA - orb275726 from Biorbyt
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PIP5KL1 shRNA Plasmid (Human) - CHJ5225 from Cohesion Biosciences
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PIP5KL1 miRNA 3'UTR clone - MiUTR1H-07928 from Creative biogene
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PIP5KL1 miRNA 3'UTR clone - MiUTR3H-12654 from Creative biogene
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