MAN1B1

Gene Symbol	MAN1B1
Entrez Gene	11253
Alt Symbol	ERMAN1, MANA-ER, MRT15
Species	Human
Gene Type	protein-coding
Description	mannosidase, alpha, class 1B, member 1
Other Description	ER alpha 1,2-mannosidase|Man9GlcNAc2-specific processing alpha-mannosidase|endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase|endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1
Swissprots	Q9Y5K7 Q9BRS9 Q5VSG3 Q9UKM7
Accessions	EAW88345 EAW88346 EAW88347 Q9UKM7 AB209276 BAD92513 AF145732 AAD45504 AF148509 AAF03215 AI312031 AK074559 BAC11060 AK074699 BAG51987 AK094878 AK126926 AK127005 AK128033 AK128257 BAG54653 AK128341 BAG54664 AK130143 AK298480 BAG60691 AK299043 BAG61117 AK309808 AK315797 AL110221 CAB53680 AY358465 AAQ88830 BC002953 AAH02953 BC006079 AAH06079 BE731944 BM848429 BQ448144 CR749534 CAH18340 DA763005 DQ891861 ABM82787 DQ895050 ABM85976 XM_006716945 XP_006717008 NM_016219 NP_057303 NR_045720 NR_045721
Function	Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2). {ECO:0000269|PubMed:12090241, ECO:0000269|PubMed:18003979}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:10409699}; Single-pass type II membrane protein {ECO:0000269|PubMed:10409699}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:10409699, ECO:0000269|PubMed:10521544}.
Top Pathways	N-Glycan biosynthesis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAN1B1 Gene cDNA Clone - orb144179 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-MAN1B1-cDNA-Clone - DC01190 from Abgent, a WuXi AppTec company Prices $943.65 Sizes 10 µg Species Human Accession BC002953

MAN1B1 - MBS1272348 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC006079

MAN1B1 - MBS1278083 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC002953

Human MAN1B1 ORF Clone(NM_016219.4) - CDCL169499 from Creative Biomart Species Human Accession NM_016219.4

Human MAN1B1 Gene ORF cDNA clone in cloning vector - HG14345-G from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14345-ACG from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14345-NY from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, C-His tag - HG14345-CH from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid - HG14345-UT from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14345-CY from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14345-NF from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14345-NM from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14345-CF from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14345-ACR from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14345-CM from Sino Biological Species Human

Human MAN1B1 Gene ORF cDNA clone expression plasmid, N-His tag - HG14345-NH from Sino Biological Species Human

Human MAN1B1 ORF Clone (BC002953) - CDCS414216 from Creative biogene Species Human Accession Q9UKM7

Human MAN1B1 ORF Clone (BC006079) - CDCS414217 from Creative biogene Species Human Accession Q9UKM7

Human MAN1B1 ORF clone (BC002953) - CDCB159158 from Creative biogene Species Human

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