Gene Symbol | CACNG2 |
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Entrez Gene | 10369 |
Alt Symbol | MRD10 |
Species | Human |
Gene Type | protein-coding |
Description | calcium channel, voltage-dependent, gamma subunit 2 |
Other Description | TARP gamma-2|neuronal voltage-gated calcium channel gamma-2 subunit|stargazin|transmembrane AMPAR regulatory protein gamma-2|voltage-dependent calcium channel gamma-2 subunit |
Swissprots | Q9Y698 Q5TGT3 Q9UGZ7 Q2M1M1 |
Accessions | EAW60113 Q9Y698 AF096322 AAD22738 AK123431 BC069612 AAH69612 BC112297 AAI12298 BC112299 AAI12300 BE670632 BI919073 CR456414 CAG30300 CU012974 CAK54405 CU013262 CAK54704 HG512270 HQ258186 ADR82940 NM_006078 NP_006069 |
Function | Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. {ECO:0000269|PubMed:20805473}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Brain. |
Top Pathways | MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
Stargazin Antibody - 2503 from Cell Signaling Technology
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Stargazin (D33G3) Rabbit mAb - 8511 from Cell Signaling Technology
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L-type Ca ++ CP γ2 (B-5) - sc-374123 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ2 (D-7) - sc-376281 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ2 (C-14) - sc-18285 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ2 (T-12) - sc-18284 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ2 (H-80) - sc-28620 from Santa Cruz Biotechnology
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Anti-Stargazin antibody - ab81105 from Abcam
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Anti-CACNG2 / Stargazin Antibody (aa305-323) - LS-C10353 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (Internal) - LS-C136392 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (C-Terminus) - LS-C132254 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody - LS-C26757 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa93-323) - LS-C185766 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1) - LS-C209516 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-36) - LS-C209518 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 488) - LS-C228822 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 390) - LS-C228823 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 565) - LS-C228824 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 633) - LS-C228826 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 594) - LS-C228825 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 655) - LS-C228827 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa129-178) - LS-C145314 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 680) - LS-C228828 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody - LS-C150332 from LifeSpan Bioscience
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Anti-CACNG2 / Stargazin Antibody (aa203-323, clone S245-1, Atto 700) - LS-C228829 from LifeSpan Bioscience
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