| Gene Symbol |
KRTAP5-6
|
| Entrez Gene |
440023
|
| Alt Symbol |
KRTAP5.6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin associated protein 5-6
|
| Other Description |
keratin-associated protein 5-6|keratin-associated protein 5.6|ultrahigh sulfur keratin-associated protein 5.6
|
| Swissprots |
A1L452 Q6L8G9
|
| Accessions |
Q6L8G9 AB126075 BAD20202 BC130399 AAI30400 BC133035 AAI33036 NM_001012416 NP_001012416
|
| Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|
| Tissue Specificity |
Expressed in hair root and not in skin. Expressed also in liver and skeletal muscle. {ECO:0000269|PubMed:15144888}.
|