Gene Symbol | KRTAP5-6 |
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Entrez Gene | 440023 |
Alt Symbol | KRTAP5.6 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 5-6 |
Other Description | keratin-associated protein 5-6|keratin-associated protein 5.6|ultrahigh sulfur keratin-associated protein 5.6 |
Swissprots | A1L452 Q6L8G9 |
Accessions | Q6L8G9 AB126075 BAD20202 BC130399 AAI30400 BC133035 AAI33036 NM_001012416 NP_001012416 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Expressed in hair root and not in skin. Expressed also in liver and skeletal muscle. {ECO:0000269|PubMed:15144888}. |
KRTAP5-6 CRISPR/Cas9 KO Plasmid (h) - sc-416342 from Santa Cruz Biotechnology
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KRTAP5-6 HDR Plasmid (h) - sc-416342-HDR from Santa Cruz Biotechnology
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KRTAP5-6 Double Nickase Plasmid (h) - sc-416342-NIC from Santa Cruz Biotechnology
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KRTAP5-6 Double Nickase Plasmid (h2) - sc-416342-NIC-2 from Santa Cruz Biotechnology
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KRTAP5-6 CRISPR Activation Plasmid (h) - sc-416342-ACT from Santa Cruz Biotechnology
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KRTAP5-6 CRISPR Activation Plasmid (h2) - sc-416342-ACT-2 from Santa Cruz Biotechnology
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KRTAP5-6 Lentiviral Activation Particles (h) - sc-416342-LAC from Santa Cruz Biotechnology
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KRTAP5-6 Lentiviral Activation Particles (h2) - sc-416342-LAC-2 from Santa Cruz Biotechnology
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KRTAP5-6 siRNA (h) - sc-96283 from Santa Cruz Biotechnology
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KRTAP5-6 shRNA Plasmid (h) - sc-96283-SH from Santa Cruz Biotechnology
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KRTAP5-6 shRNA (h) Lentiviral Particles - sc-96283-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11486 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11486 from Sigma-Aldrich
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KRTAP5-6 siRNA (Human) - CRJ8226 from Cohesion Biosciences
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Human KRTAP5-6 siRNA - orb278727 from Biorbyt
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KRTAP5-6 shRNA Plasmid (Human) - CHJ8226 from Cohesion Biosciences
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KRTAP5-6 miRNA 3'UTR clone - MiUTR1H-05526 from Creative biogene
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