| Gene Symbol |
KATNAL1
|
| Entrez Gene |
84056
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
katanin p60 subunit A-like 1
|
| Other Description |
katanin p60 ATPase-containing subunit A-like 1|p60 katanin-like 1
|
| Swissprots |
Q9BW62 A8K5X4
|
| Accessions |
EAX08452 EAX08453 Q9BW62 AK097423 BAG53469 AK291439 BAF84128 AK315724 BAG38080 AW019882 BC000612 AAH00612 BX647147 DA085487 DQ892639 ABM83565 DQ895877 ABM86803 DR006891 XM_005266574 XP_005266631 XM_006719881 XP_006719944 XM_011535278 XP_011533580 XM_011535279 XP_011533581 NM_001014380 NP_001014402 NM_032116 NP_115492
|
| Function |
Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000255|HAMAP- Rule:MF_03024, ECO:0000269|PubMed:22654668}.
|
| Tissue Specificity |
Expressed in testis, restricted to Sertoli cells (at protein level). {ECO:0000269|PubMed:22654668}.
|