Gene Symbol | KATNAL1 |
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Entrez Gene | 84056 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | katanin p60 subunit A-like 1 |
Other Description | katanin p60 ATPase-containing subunit A-like 1|p60 katanin-like 1 |
Swissprots | Q9BW62 A8K5X4 |
Accessions | EAX08452 EAX08453 Q9BW62 AK097423 BAG53469 AK291439 BAF84128 AK315724 BAG38080 AW019882 BC000612 AAH00612 BX647147 DA085487 DQ892639 ABM83565 DQ895877 ABM86803 DR006891 XM_005266574 XP_005266631 XM_006719881 XP_006719944 XM_011535278 XP_011533580 XM_011535279 XP_011533581 NM_001014380 NP_001014402 NM_032116 NP_115492 |
Function | Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000255|HAMAP- Rule:MF_03024, ECO:0000269|PubMed:22654668}. |
Tissue Specificity | Expressed in testis, restricted to Sertoli cells (at protein level). {ECO:0000269|PubMed:22654668}. |
Katanin p60 AL1 CRISPR/Cas9 KO Plasmid (h) - sc-404646 from Santa Cruz Biotechnology
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Katanin p60 AL1 HDR Plasmid (h) - sc-404646-HDR from Santa Cruz Biotechnology
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Katanin p60 AL1 Double Nickase Plasmid (h) - sc-404646-NIC from Santa Cruz Biotechnology
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Katanin p60 AL1 Double Nickase Plasmid (h2) - sc-404646-NIC-2 from Santa Cruz Biotechnology
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Katanin p60 AL1 CRISPR Activation Plasmid (h) - sc-404646-ACT from Santa Cruz Biotechnology
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Katanin p60 AL1 CRISPR Activation Plasmid (h2) - sc-404646-ACT-2 from Santa Cruz Biotechnology
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Katanin p60 AL1 Lentiviral Activation Particles (h) - sc-404646-LAC from Santa Cruz Biotechnology
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Katanin p60 AL1 Lentiviral Activation Particles (h2) - sc-404646-LAC-2 from Santa Cruz Biotechnology
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Katanin p60 AL1 siRNA (h) - sc-75364 from Santa Cruz Biotechnology
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Katanin p60 AL1 shRNA Plasmid (h) - sc-75364-SH from Santa Cruz Biotechnology
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Katanin p60 AL1 shRNA (h) Lentiviral Particles - sc-75364-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU052081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10899 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10899 from Sigma-Aldrich
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KATNAL1 siRNA (Human) - CRJ3269 from Cohesion Biosciences
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KATNAL1, siRNA - MBS8216463 from MyBioSource
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shRNA set against Human KATNAL1 (NM_032116.4) - SHH322479 from Creative biogene
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Human KATNAL1 siRNA - orb273770 from Biorbyt
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KATNAL1 shRNA Plasmid (Human) - CHJ3269 from Cohesion Biosciences
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