ACSBG1

Gene Symbol ACSBG1
Entrez Gene 23205
Alt Symbol BG, BG1, BGM, GR-LACS, LPD
Species Human
Gene Type protein-coding
Description acyl-CoA synthetase bubblegum family member 1
Other Description bubblegum|lipidosin|long-chain-fatty-acid--CoA ligase ACSBG1|very long-chain acyl-CoA synthetase
Swissprots Q96GR2 Q9HC26 O75126 B2RB61 Q76N27
Accessions CBF65091 CBU89962 EAW99180 Q96GR2 AF070624 AF179481 AAG09404 AK054882 BAG51439 AK294202 BAH11696 AK295269 BAH12022 AK299597 BAH13077 AK314508 BAG37108 BC009289 AAH09289 BC040252 DC401742 DQ896428 ABM87427 EU176436 ABW03887 XM_011521389 XP_011519691 XM_011521390 XP_011519692 XM_011521391 XP_011519693 NM_001199377 NP_001186306 NM_015162 NP_055977
Function Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. {ECO:0000269|PubMed:10954726, ECO:0000269|PubMed:12975357}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10954726}. Cytoplasmic vesicle {ECO:0000250}. Microsome {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Tissue Specificity Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary. {ECO:0000269|PubMed:10954726, ECO:0000269|PubMed:12975357}.
Top Pathways Adipocytokine signaling pathway, PPAR signaling pathway, Fatty acid biosynthesis, Fatty acid degradation, Fatty acid metabolism

ACSBG1 (G-14) - sc-162474 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACSBG1 (S-15) - sc-162475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACSBG1 (Y-17) - sc-162476 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACSBG1 (Y-17): sc-162476. Western blot analysis of ACSBG1 expression in non-transfected: sc-117752 (A) and human ACSBG1 transfected: sc-171703 (B) 293T whole cell lysates.

Anti-ACSBG1 antibody - ab65154 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSBG1 antibody - ab172410 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ACSBG1 antibody (ab172410) at 1 µg/mlLane 1 : ACSBG1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-ACSBG1 antibody [2B6] - ab118154 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B6
Overlay histogram showing SH-SY5Y cells stained with ab118154 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab118154, 1/100 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-ACSBG1 antibody - N-terminal - ab186619 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ACSBG1 antibody - N-terminal (ab186619) at 1 µg/ml + HT1080 cell lysate at 10 µg

Anti-BG-1 antibody [061006-11E3] - ab169791 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 061006-11E3
Immunohistochemical analysis of Human normal ovarian tissue labeling BG-1 with ab169791 at 1/500.

Anti-BG-1 antibody [061006-3C8] - ab169802 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 061006-3C8
Immunohistochemical analysis of Human ovarian epithelial tissue (normal) labeling BG-1 with ab169802 at 1/50.

Anti-BG-1 antibody [070126-14C6] - ab169797 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 070126-14C6
Immunohistochemical analysis of Human CAOV-3 ovarian cell line labeling BG-1 with ab169797 at 1/600.

Anti-BG-1 antibody [100913-1B1] - ab169800 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 100913-1B1
Immunohistochemical analysis of Human colon carcinoma tissue labeling BG-1 with ab169800 at 1/2000.

Anti-ACSBG1 / hsBG Antibody (clone 2B6) - LS-C115210 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B6
IHC of paraffin-embedded liver tissue using anti-ACSBG1 mouse monoclonal antibody. (Dilution 1:50).

Anti-ACSBG1 / hsBG Antibody (clone 1D8) - LS-C115217 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D8
IHC of paraffin-embedded Carcinoma of prostate tissue using anti-ACSBG1 mouse monoclonal antibody. (Dilution 1:50).

Anti-ACSBG1 / hsBG Antibody - LS-C306065 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ACSBG1 / hsBG Antibody (aa509-558) - LS-C201755 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human HT1080. ACSBG1 antibody dilution 1.0 ug/ml.

Anti-ACSBG1 / hsBG Antibody (aa15-64) - LS-C205831 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ACSBG1 / hsBG antibody Western Blot of HT1080. Antibody dilution: 1 ug/ml.

ACSBG1 Antibody (1D8) - NBP2-02554 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D8
Western Blot: ACSBG1 Antibody (1D8) [NBP2-02554] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSBG1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSBG1.

ACSBG1 Antibody - NBP2-31990 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: ACSBG1 Antibody [NBP2-31990] - Staining of human adrenal gland shows strong cytoplasmic positivity in cortical cells.

ACSBG1 Antibody - NBP1-18715 from Novus Biologicals

Prices $329.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

ACSBG1 Antibody - H00023205-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ACSBG1 Antibody [H00023205-B01] - analysis of ACSBG1 expression in transfected 293T cell line by ACSBG1 MaxPab polyclonal antibody (B01). Lane 1: ACSBG1 transfected lysate (81.30 KDa). Lane 2: Non-transfected lysate.

ACSBG1 Antibody - H00023205-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ACSBG1 Antibody [H00023205-B01P] - Analysis of ACSBG1 expression in transfected 293T cell line by ACSBG1 polyclonal antibody. Lane 1: ACSBG1 transfected lysate(79.64 KDa). Lane 2: Non-transfected lysate.

Anti-ACSBG1 antibody produced in rabbit - HPA041642 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ACSBG1: <B>Cat. No. HPA041642</B>: Immunohistochemical staining of Human adrenal gland shows strong cytoplasmic positivity in cortical cells.

Monoclonal Anti-ACSBG1 antibody produced in mouse - SAB4100015 from Sigma-Aldrich

Prices $377.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone ACSBG1-A18
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells expressing FLAG<SUP>®</SUP>-tagged human ACSBG1 was separated on SDS-PAGE, probed with Mouse Anti-ACSBG1 Clone: ACSBG1-A18 (<B>Cat. No. SAB4100015</B>). The antibody was developed using Goat Anti-Mouse IgG-Peroxidase (<B>Cat. No. A2304</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500<BR/>2. Antibody dilution 1:1,000<BR/>3. Negative control<BR/>4. Positive control Anti-FLAG<SUP>®</SUP>

Anti-ACSBG1 antibody produced in mouse - SAB1407184 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ACSBG1: <B>Cat. No. SAB1407184</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~79.6 kDa using ACSBG1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-ACSBG1 (21-35) antibody produced in rabbit - SAB1101324 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti- ACSBG1 (21-35) (RB): <B>Cat. No. SAB1101324</B>: Immunofluorescence of HUVEC cells using Anti-ACSBG1 (21-35) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com
Search more