| Gene Symbol |
ACSBG1
|
| Entrez Gene |
23205
|
| Alt Symbol |
BG, BG1, BGM, GR-LACS, LPD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
acyl-CoA synthetase bubblegum family member 1
|
| Other Description |
bubblegum|lipidosin|long-chain-fatty-acid--CoA ligase ACSBG1|very long-chain acyl-CoA synthetase
|
| Swissprots |
Q96GR2 Q9HC26 O75126 B2RB61 Q76N27
|
| Accessions |
CBF65091 CBU89962 EAW99180 Q96GR2 AF070624 AF179481 AAG09404 AK054882 BAG51439 AK294202 BAH11696 AK295269 BAH12022 AK299597 BAH13077 AK314508 BAG37108 BC009289 AAH09289 BC040252 DC401742 DQ896428 ABM87427 EU176436 ABW03887 XM_011521389 XP_011519691 XM_011521390 XP_011519692 XM_011521391 XP_011519693 NM_001199377 NP_001186306 NM_015162 NP_055977
|
| Function |
Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. {ECO:0000269|PubMed:10954726, ECO:0000269|PubMed:12975357}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:10954726}. Cytoplasmic vesicle {ECO:0000250}. Microsome {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
|
| Tissue Specificity |
Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary. {ECO:0000269|PubMed:10954726, ECO:0000269|PubMed:12975357}.
|
| Top Pathways |
Adipocytokine signaling pathway, PPAR signaling pathway, Fatty acid biosynthesis, Fatty acid degradation, Fatty acid metabolism
|