| Gene Symbol |
ADRB2
|
| Entrez Gene |
154
|
| Alt Symbol |
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adrenoceptor beta 2, surface
|
| Other Description |
adrenergic, beta-2-, receptor, surface|adrenoceptor beta 2 surface|beta-2 adrenergic receptor|beta-2 adrenoceptor|beta-2 adrenoreceptor|catecholamine receptor
|
| Swissprots |
Q9UCZ3 Q6P4D8 Q9UH95 Q8NEQ9 P07550 Q53GA6 Q9UMZ5 Q9UCZ1 Q4JG18 Q96EC3 B0LPE4 O14826 Q9UHA1 Q9UCZ0 Q6GMT4 O14825 O14823 O14824 B2R7X2 Q9UCZ2
|
| Accessions |
AAA88017 AAB82148 AAB82149 AAB82150 AAB82151 AAD48036 AAF17569 AAF20199 AAG35451 AAY88739 ABY87523 CAA68289 CBJ06537 EAW61798 P07550 AA886615 AK223025 BAD96745 AK313151 BAG35969 AY136741 AAN01267 BC012481 AAH12481 BC063486 AAH63486 BC073856 AAH73856 DA705141 KJ534762 AHW56402 M15169 AAA88014 X04827 CAA28511 NM_000024 NP_000015
|
| Function |
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:19584355}; Multi-pass membrane protein {ECO:0000269|PubMed:19584355}. Note=Colocalizes with VHL at the cell membrane.
|
| Top Pathways |
Calcium signaling pathway, Endocytosis, Salivary secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway
|
![Western Blot: Beta 2 Adrenergic Receptor Overexpression Lysate (Adult Normal) [NBP2-11173] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Beta 2 Adrenergic Receptor.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/25916_Beta%25202%2520Adrenergic%2520Receptor%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-11173-img0001.jpg)