ANP32A

Gene Symbol ANP32A
Entrez Gene 8125
Alt Symbol C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32
Species Human
Gene Type protein-coding
Description acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Other Description acidic leucine-rich nuclear phosphoprotein 32 family member A|acidic nuclear phosphoprotein pp32|cerebellar leucine rich acidic nuclear protein|hepatopoietin Cn|inhibitor-1 of protein phosphatase-2A|leucine-rich acidic nuclear protein|mapmodulin|potent heat-stable protein phosphatase 2A inhibitor I1PP2A|putative HLA-DR-associated protein I|putative human HLA class II associated protein I
Swissprots Q5J8L8 B2R6T4 Q7M4N6 Q53FK4 P39687
Accessions EAW77824 EAW77825 P39687 AF025684 AAB91548 AK127498 AK223280 BAD97000 AK312703 BAG35581 AW383928 AY007110 AY349171 AAQ79832 BC000608 AAH00608 BC007200 AAH07200 BC064969 BC106719 AAI06720 BC125143 AAI25144 BT007436 AAP36104 DA825897 DQ893294 ABM84220 DQ896729 ABM87728 U60823 AAC50570 U73477 AAB39706 X75090 CAA52981 XM_006720707 XP_006720770 NM_006305 NP_006296
Function Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression. {ECO:0000269|PubMed:10400610, ECO:0000269|PubMed:11360199, ECO:0000269|PubMed:15642345, ECO:0000269|PubMed:17557114}.
Subcellular Location Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Translocates to the cytoplasm during the process of neuritogenesis (By similarity). Shuttles between nucleus and cytoplasm. {ECO:0000250}.
Tissue Specificity Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala. {ECO:0000269|PubMed:15642345}.

ANP32A (C-18) - sc-5652 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ANP32A (C-18): sc-5652. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human brain tumor showing nuclear staining.

ANP32A (A-182) - sc-100767 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
ANP32A (A-182): sc-100767. Western blot analysis of ANP32A expression in HeLa whole cell lysate.

Anti-PHAP1 antibody - ab5991 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of PHAP I expression in human Raji cell (A), mouse (B) and rat (C) testis tissue llysates with anti-PHAP I at 1 µg/ml

Anti-PHAP1 antibody - ab5992 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of PHAP I expression in human Raji cell lysate with anti-PHAP I at 2 µg/ml (lane A) and 4 µg/ml (lane B), respectively.

Anti-PHAP1 antibody - ab56429 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
PHAP1 antibody (ab56429) used in immunofluorescence at 1-5ug/ml on HeLa cells.

Anti-PHAP1 antibody - ab1181 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Western blot of 10 µg HEK 293 cell extracts with Anti- I1α (GLO149). The band corresponds to I1αPP2A (~ 30 kDa).

Anti-PHAP1 antibody - C-terminal - ab189110 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labelling PHAP1 with ab189110 at 10 µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-PHAP1 / ANP32A Antibody (N-Terminus) IHC-plus™ - LS-B3194 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ANP32A antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3194 concentration 5 ug/ml.

Anti-PHAP1 / ANP32A Antibody (C-Terminus) IHC-plus™ - LS-B3195 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ANP32A antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3195 concentration 5 ug/ml.

Anti-PHAP1 / ANP32A Antibody - LS-C18698 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PHAP1 / ANP32A Antibody (aa87-103) - LS-C728 from LifeSpan Bioscience

Prices $335.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Western blot detection of INHAT-2 using antibody at a 1:1000 dilution against 10 ug of HeLa cell lysate.

Anti-PHAP1 / ANP32A Antibody (N-Terminus) - LS-C30659 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ANP32A antibody LS-C30659 was used in IHC to stain formalin-fixed, paraffin-embedded human heart.

Anti-PHAP1 / ANP32A Antibody (aa26-55) - LS-C190992 from LifeSpan Bioscience

Prices $575.00
Sizes 400 µg
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (aa26-55) - LS-C190991 from LifeSpan Bioscience

Prices $405.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (clone GF1) - LS-C190309 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-PHAP1 / ANP32A Antibody (aa133-162, FITC) - LS-C251391 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (aa133-162, Biotin) - LS-C251392 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (aa133-162, AP) - LS-C251389 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (aa133-162, Azide-free, HRP) - LS-C251393 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (aa133-162, APC) - LS-C251390 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (aa133-162, PE) - LS-C251395 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (clone 8D2) - LS-C171326 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8D2
IHC of paraffin-embedded human kidney tissue using PP32 mouse mAb with DAB staining.

Anti-PHAP1 / ANP32A Antibody (C-Terminus) - LS-C431 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of PHAP I in Raji cells with PHAP I antibody at 2 ug/ml.

Anti-PHAP1 / ANP32A Antibody (aa2-247, Biotin) - LS-C297263 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PHAP1 / ANP32A Antibody (aa2-249, Biotin) - LS-C299169 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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