| Gene Symbol |
SLC48A1
|
| Entrez Gene |
55652
|
| Alt Symbol |
HRG-1, HRG1, hHRG-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 48 (heme transporter), member 1
|
| Other Description |
heme transporter HRG1|heme-responsive gene 1 protein homolog|solute carrier family 48 member 1
|
| Swissprots |
Q9BUB3 Q9NX17 Q6P1K1
|
| Accessions |
EAW57950 EAW57951 Q6P1K1 AK000496 BAA91205 AK025856 AK294075 BAG57417 BC002759 AAH02759 BC011823 BC026344 AAH26344 BC065033 AAH65033 BI548780 XM_005269016 XP_005269073 XM_011538557 XP_011536859 XM_011538558 XP_011536860 NM_017842 NP_060312
|
| Function |
Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. {ECO:0000269|PubMed:18418376}.
|
| Subcellular Location |
Endosome membrane {ECO:0000269|PubMed:18418376}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}. Lysosome membrane {ECO:0000269|PubMed:18418376}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}.
|
| Tissue Specificity |
Highly expressed in the brain, kidney, heart and skeletal muscle. Moderately expressed in the liver, lung, placenta and small intestine. {ECO:0000269|PubMed:18418376}.
|