Gene Symbol | SLC48A1 |
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Entrez Gene | 55652 |
Alt Symbol | HRG-1, HRG1, hHRG-1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 48 (heme transporter), member 1 |
Other Description | heme transporter HRG1|heme-responsive gene 1 protein homolog|solute carrier family 48 member 1 |
Swissprots | Q9BUB3 Q9NX17 Q6P1K1 |
Accessions | EAW57950 EAW57951 Q6P1K1 AK000496 BAA91205 AK025856 AK294075 BAG57417 BC002759 AAH02759 BC011823 BC026344 AAH26344 BC065033 AAH65033 BI548780 XM_005269016 XP_005269073 XM_011538557 XP_011536859 XM_011538558 XP_011536860 NM_017842 NP_060312 |
Function | Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. {ECO:0000269|PubMed:18418376}. |
Subcellular Location | Endosome membrane {ECO:0000269|PubMed:18418376}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}. Lysosome membrane {ECO:0000269|PubMed:18418376}; Multi-pass membrane protein {ECO:0000269|PubMed:18418376}. |
Tissue Specificity | Highly expressed in the brain, kidney, heart and skeletal muscle. Moderately expressed in the liver, lung, placenta and small intestine. {ECO:0000269|PubMed:18418376}. |
SLC48A1 CRISPR/Cas9 KO Plasmid (h) - sc-405746 from Santa Cruz Biotechnology
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SLC48A1 HDR Plasmid (h) - sc-405746-HDR from Santa Cruz Biotechnology
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SLC48A1 Double Nickase Plasmid (h) - sc-405746-NIC from Santa Cruz Biotechnology
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SLC48A1 Double Nickase Plasmid (h2) - sc-405746-NIC-2 from Santa Cruz Biotechnology
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SLC48A1 CRISPR Activation Plasmid (h) - sc-405746-ACT from Santa Cruz Biotechnology
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SLC48A1 CRISPR Activation Plasmid (h2) - sc-405746-ACT-2 from Santa Cruz Biotechnology
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SLC48A1 Lentiviral Activation Particles (h) - sc-405746-LAC from Santa Cruz Biotechnology
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SLC48A1 Lentiviral Activation Particles (h2) - sc-405746-LAC-2 from Santa Cruz Biotechnology
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SLC48A1 siRNA (h) - sc-95722 from Santa Cruz Biotechnology
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SLC48A1 shRNA Plasmid (h) - sc-95722-SH from Santa Cruz Biotechnology
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SLC48A1 shRNA (h) Lentiviral Particles - sc-95722-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN19650 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19650 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05901 from Sigma-Aldrich
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SLC48A1 siRNA (Human) - CRJ0804 from Cohesion Biosciences
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SLC48A1 - MBS8228998 from MyBioSource
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SLC48A1 CRISPR/Cas9 KO Plasmid (h2) - sc-405746-KO-2 from Santa Cruz Biotechnology
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SLC48A1 HDR Plasmid (h2) - sc-405746-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human SLC48A1 (NM_017842.2) - SHH411488 from Creative biogene
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SLC48A1 shRNA Plasmid (Human) - CHJ0804 from Cohesion Biosciences
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SLC48A1 miRNA 3'UTR clone - MiUTR4H-TG08282 from Creative biogene
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