Gene Symbol | HMGN5 |
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Entrez Gene | 79366 |
Alt Symbol | NBP-45, NSBP1 |
Species | Human |
Gene Type | protein-coding |
Description | high mobility group nucleosome binding domain 5 |
Other Description | high mobility group nucleosome-binding domain-containing protein 5|high-mobility group nucleosome binding domain 5|nucleosomal binding protein 1|nucleosome-binding protein 1 |
Swissprots | P82970 Q5JSL1 |
Accessions | AAK14063 EAW98582 P82970 AF250329 AAK14062 AK094058 AK315792 BAG38137 BC005342 AAH05342 DA745749 EU446988 ABZ92517 XM_006724688 XP_006724751 XM_006724689 XP_006724752 XM_006724690 XP_006724753 NM_030763 NP_110390 |
Function | Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11161810}. Note=Associates with nucleosomes in euchromatin and is largely excluded from constitutive heterochromatin. {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:11161810}. |
NSBP1 CRISPR/Cas9 KO Plasmid (h) - sc-416473 from Santa Cruz Biotechnology
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NSBP1 HDR Plasmid (h) - sc-416473-HDR from Santa Cruz Biotechnology
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NSBP1 Double Nickase Plasmid (h) - sc-416473-NIC from Santa Cruz Biotechnology
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NSBP1 Double Nickase Plasmid (h2) - sc-416473-NIC-2 from Santa Cruz Biotechnology
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NSBP1 CRISPR Activation Plasmid (h) - sc-416473-ACT from Santa Cruz Biotechnology
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NSBP1 CRISPR Activation Plasmid (h2) - sc-416473-ACT-2 from Santa Cruz Biotechnology
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NSBP1 Lentiviral Activation Particles (h) - sc-416473-LAC from Santa Cruz Biotechnology
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NSBP1 Lentiviral Activation Particles (h2) - sc-416473-LAC-2 from Santa Cruz Biotechnology
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NSBP1 siRNA (h) - sc-90899 from Santa Cruz Biotechnology
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NSBP1 shRNA Plasmid (h) - sc-90899-SH from Santa Cruz Biotechnology
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NSBP1 shRNA (h) Lentiviral Particles - sc-90899-V from Santa Cruz Biotechnology
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NSBP1 RNAi - H00079366-R01 from Novus Biologicals
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MISSION® esiRNA - EHU083251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10174 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10174 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07458 from Sigma-Aldrich
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HMGN5 siRNA (Human) - CRJ2374 from Cohesion Biosciences
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HMGN5 - MBS8230501 from MyBioSource
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shRNA set against Human HMGN5 (NM_030763.2) - SHH313469 from Creative biogene
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HMGN5 shRNA Plasmid (Human) - CHJ2374 from Cohesion Biosciences
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HMGN5 miRNA 3'UTR clone - MiUTR4H-TG11446 from Creative biogene
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