Gene Symbol | RFXANK |
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Entrez Gene | 8625 |
Alt Symbol | ANKRA1, BLS, F14150_1, RFX-B |
Species | Human |
Gene Type | protein-coding |
Description | regulatory factor X-associated ankyrin-containing protein |
Other Description | DNA-binding protein RFXANK|RFX-Bdelta4|ankyrin repeat family A protein 1|ankyrin repeat-containing regulatory factor X-associated protein|regulatory factor X subunit B |
Swissprots | Q24JQ1 O95839 Q6FGA8 O14593 |
Accessions | AAB86654 CAC09014 CDL97006 CDL97007 EAW84795 EAW84796 EAW84797 EAW84798 EAW84799 O14593 AF077196 AAD26991 AF094760 AAC69883 AF105427 AAD17972 AF105428 AAD17973 AW411190 AW411361 BC114558 AAI14559 BC114563 AAI14564 BG740813 BM682278 BM712354 CR456981 CAG33262 CR542199 CAG46996 CX871218 X75690 XM_005260134 XP_005260191 XM_005260135 XP_005260192 XM_005260136 XP_005260193 XM_005260137 XP_005260194 XM_006722930 XP_006722993 NM_001278727 NP_001265656 NM_001278728 NP_001265657 NM_003721 NP_003712 NM_134440 NP_604389 |
Function | Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes. |
Subcellular Location | Nucleus. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Primary immunodeficiency, Tuberculosis, Antigen processing and presentation |
RFX-B (E-18) - sc-9823 from Santa Cruz Biotechnology
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RFX-B (H-70) - sc-366815 from Santa Cruz Biotechnology
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RFX-B (C-18) - sc-9821 from Santa Cruz Biotechnology
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Anti-RFXANK antibody - ab9257 from Abcam
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Anti-RFXANK antibody - ab124068 from Abcam
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Anti-RFXANK antibody [3B4] - ab131574 from Abcam
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Anti-RFXANK antibody [3C10] - ab119432 from Abcam
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Anti-RFXANK antibody (Agarose) - ab19200 from Abcam
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Anti-RFXANK Antibody - LS-C3730 from LifeSpan Bioscience
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Anti-RFXANK Antibody - LS-C3732 from LifeSpan Bioscience
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Anti-RFXANK Antibody - LS-C3733 from LifeSpan Bioscience
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Anti-RFXANK Antibody (aa18-31) - LS-C40575 from LifeSpan Bioscience
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Anti-RFXANK Antibody (C-Terminus) - LS-C90991 from LifeSpan Bioscience
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Anti-RFXANK Antibody (Agarose) - LS-C90992 from LifeSpan Bioscience
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Anti-RFXANK Antibody - LS-C2876 from LifeSpan Bioscience
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Anti-RFXANK Antibody (aa94-123, AP) - LS-C239936 from LifeSpan Bioscience
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Anti-RFXANK Antibody (aa94-123, APC) - LS-C239937 from LifeSpan Bioscience
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Anti-RFXANK Antibody (aa94-123, Biotin) - LS-C239938 from LifeSpan Bioscience
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Anti-RFXANK Antibody (aa94-123, FITC) - LS-C239939 from LifeSpan Bioscience
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Anti-RFXANK Antibody (clone 2B6) - LS-C173731 from LifeSpan Bioscience
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Anti-RFXANK Antibody (clone 2F12) - LS-C173730 from LifeSpan Bioscience
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Anti-RFXANK Antibody (clone 3E7) - LS-C337623 from LifeSpan Bioscience
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Anti-RFXANK Antibody (aa94-123, Azide-free, HRP) - LS-C248647 from LifeSpan Bioscience
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Anti-RFXANK Antibody (aa94-123, PE) - LS-C239942 from LifeSpan Bioscience
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Anti-RFXANK Antibody (C-Terminus) - LS-C286976 from LifeSpan Bioscience
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