Gene Symbol | FGF7 |
---|---|
Entrez Gene | 2252 |
Alt Symbol | HBGF-7, KGF |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 7 |
Other Description | FGF-7|heparin-binding growth factor 7|keratinocyte growth factor |
Swissprots | P21781 Q96FG5 Q6FGV5 H0YNY5 |
Accessions | EAW77376 P21781 AK313160 BAG35978 BC010956 AAH10956 CR542002 CAG46799 DB206350 M60828 AAA63210 S81661 AAB21431 NM_002009 NP_002000 |
Function | Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. {ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:8663044}. |
Subcellular Location | Secreted. |
Tissue Specificity | Epithelial cell. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |