Gene Symbol | FGF7 |
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Entrez Gene | 2252 |
Alt Symbol | HBGF-7, KGF |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 7 |
Other Description | FGF-7|heparin-binding growth factor 7|keratinocyte growth factor |
Swissprots | P21781 Q96FG5 Q6FGV5 H0YNY5 |
Accessions | EAW77376 P21781 AK313160 BAG35978 BC010956 AAH10956 CR542002 CAG46799 DB206350 M60828 AAA63210 S81661 AAB21431 NM_002009 NP_002000 |
Function | Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. {ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:8663044}. |
Subcellular Location | Secreted. |
Tissue Specificity | Epithelial cell. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF-7 CRISPR/Cas9 KO Plasmid (h) - sc-401243 from Santa Cruz Biotechnology
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FGF-7 HDR Plasmid (h) - sc-401243-HDR from Santa Cruz Biotechnology
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FGF-7 Double Nickase Plasmid (h) - sc-401243-NIC from Santa Cruz Biotechnology
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FGF-7 Double Nickase Plasmid (h2) - sc-401243-NIC-2 from Santa Cruz Biotechnology
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FGF-7 CRISPR Activation Plasmid (h) - sc-401243-ACT from Santa Cruz Biotechnology
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FGF-7 CRISPR Activation Plasmid (h2) - sc-401243-ACT-2 from Santa Cruz Biotechnology
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FGF-7 Lentiviral Activation Particles (h) - sc-401243-LAC from Santa Cruz Biotechnology
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FGF-7 Lentiviral Activation Particles (h2) - sc-401243-LAC-2 from Santa Cruz Biotechnology
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FGF-7 siRNA (h) - sc-39456 from Santa Cruz Biotechnology
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FGF-7 shRNA Plasmid (h) - sc-39456-SH from Santa Cruz Biotechnology
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FGF-7 shRNA (h) Lentiviral Particles - sc-39456-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU051641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8664 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8664 from Sigma-Aldrich
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FGF7 siRNA (Human) - CRH1572 from Cohesion Biosciences
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FGF7 - MBS8229025 from MyBioSource
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FGF-7 CRISPR/Cas9 KO Plasmid (h2) - sc-401243-KO-2 from Santa Cruz Biotechnology
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FGF-7 HDR Plasmid (h2) - sc-401243-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human FGF7 (NM_002009.3) - SHH294589 from Creative biogene
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FGF7 shRNA Plasmid (Human) - CHH1572 from Cohesion Biosciences
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FGF7 miRNA 3'UTR clone - MiUTR4H-TG11216 from Creative biogene
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