CLPX

Gene Symbol CLPX
Entrez Gene 10845
Alt Symbol -
Species Human
Gene Type protein-coding
Description caseinolytic mitochondrial matrix peptidase chaperone subunit
Other Description ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial|ClpX caseinolytic peptidase X homolog|ClpX caseinolytic protease X homolog|energy-dependent regulator of proteolysis
Swissprots A8K8F1 B9EGI8 O76031 Q9H4D9 A1L428
Accessions CAC01291 EAW77715 EAW77716 O76031 AJ006267 CAA06933 AK292316 BAF85005 AK308133 AK310614 AL136922 CAB66856 BC130373 AAI30374 BC136487 AAI36488 BC144166 XM_011521164 XP_011519466 XR_931743 NM_006660 NP_006651
Function ATP-dependent specificity component of the Clp protease complex. Hydrolyzes ATP. Targets specific substrates for degradation by the Clp complex. Can perform chaperone functions in the absence of CLPP. Enhances the DNA-binding activity of TFAM and is required for maintaining a normal mitochondrial nucleoid structure. {ECO:0000269|PubMed:11923310, ECO:0000269|PubMed:22710082, ECO:0000269|PubMed:22841477}.
Subcellular Location Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Tissue Specificity Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas. {ECO:0000269|PubMed:11003706}.

CLPX CRISPR/Cas9 KO Plasmid (h) - sc-408816 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX HDR Plasmid (h) - sc-408816-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX Double Nickase Plasmid (h) - sc-408816-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX Double Nickase Plasmid (h2) - sc-408816-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX CRISPR Activation Plasmid (h) - sc-408816-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX CRISPR Activation Plasmid (h2) - sc-408816-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX Lentiviral Activation Particles (h) - sc-408816-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX Lentiviral Activation Particles (h2) - sc-408816-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLPX siRNA (h) - sc-89961 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLPX shRNA Plasmid (h) - sc-89961-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLPX shRNA (h) Lentiviral Particles - sc-89961-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLPX RNAi - H00010845-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU056501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6260 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6260 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLPX siRNA (Human) - CRH7385 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLPX - MBS8223313 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLPX (NM_006660.3) - SHH265637 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CLPX(NM_006660.3) - SHG184141 from Creative biogene

Category siRNA
Species Reactivities Human

CLPX shRNA Plasmid (Human) - CHH7385 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLPX miRNA 3'UTR clone - MiUTR1H-02236 from Creative biogene

Species Reactivities Human
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