Pitpnm1

Gene Symbol Pitpnm1
Entrez Gene 18739
Alt Symbol DRES9, Mpt-1, Nir-2, PITPnm 1, Pitpnm, R75447, Rd9, RdgB, RdgB1
Species Mouse
Gene Type protein-coding
Description phosphatidylinositol transfer protein, membrane-associated 1
Other Description drosophila retinal degeneration B homolog 1|membrane-associated phosphatidylinositol transfer protein 1|pyk2 N-terminal domain-interacting receptor 2|retinal degeneration 9
Swissprots O35954
Accessions EDL33005 EDL33006 O35954 AF006467 AAB84393 AK155377 AK177924 AK179862 AK180862 AK181080 AK183265 AK185797 AK185978 AK187966 AK188056 AK188396 AK188611 AK189965 AK190036 AK191918 AK193202 AK197131 AK200548 AK200663 AK203273 AK203300 AK203418 AK204841 AK207185 AK208861 AK209641 AK210105 AK210471 AK212016 AK212060 AK212517 AK217085 AK218358 AK219948 BC044893 AAH44893 BC048150 AAH48150 BY245171 BY261372 CJ097166 X98655 Y08922 CAA70127 XM_006531680 XP_006531743 XM_011251509 XP_011249811 XR_388251 XR_388252 XR_882621 XR_882622 NM_001136078 NM_008851 NP_032877 NR_075078
Function Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Golgi apparatus, Golgi stack membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Lipid droplet {ECO:0000250}. Cleavage furrow {ECO:0000250}. Midbody {ECO:0000250}. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets. Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis (By similarity). {ECO:0000250}.
Tissue Specificity Detected at high levels in brain, and at lower levels in lung, kidney, spleen and liver (at protein level). Ubiquitous. Highly expressed in embryonic retina and the central nervous system. {ECO:0000269|PubMed:9245688, ECO:0000269|PubMed:9680295}.

Nir2 CRISPR/Cas9 KO Plasmid (m) - sc-422251 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 HDR Plasmid (m) - sc-422251-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 Double Nickase Plasmid (m) - sc-422251-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 Double Nickase Plasmid (m2) - sc-422251-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 CRISPR Activation Plasmid (m) - sc-422251-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 CRISPR Activation Plasmid (m2) - sc-422251-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 Lentiviral Activation Particles (m) - sc-422251-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 Lentiviral Activation Particles (m2) - sc-422251-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nir2 siRNA (m) - sc-40854 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Nir2 shRNA Plasmid (m) - sc-40854-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Nir2 shRNA (m) Lentiviral Particles - sc-40854-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN38774 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38774 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PITPNM1 siRNA (Mouse) - CRM3075 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse PITPNM1 (NM_008851.3) - SHH376192 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Pitpnm1(NM_008851.3) - SHR116136 from Creative biogene

Category siRNA
Species Reactivities Mouse

PITPNM1 shRNA Plasmid (Mouse) - CHM3075 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

PITPNM1 miRNA 3'UTR clone - MiUTR1M-09242 from Creative biogene

Species Reactivities Mouse
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