| Gene Symbol | OXSM |
|---|---|
| Entrez Gene | 54995 |
| Alt Symbol | FASN2D, KASI, KS |
| Species | Human |
| Gene Type | protein-coding |
| Description | 3-oxoacyl-ACP synthase, mitochondrial |
| Other Description | 3-ketoacyl-acyl carrier protein synthase|3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial|3-oxoacyl-acyl-carrier-protein synthase|acyl-malonyl acyl carrier protein-condensing enzyme|beta-ketoacyl synthase|beta-ketoacyl-ACP synthase|type II mitochondrial beta-ketoacyl synthase |
| Swissprots | Q9NWU1 |
| Accessions | CAD22819 CAD22820 CBN69072 CBN70680 EAW64367 EAW64368 EAW64369 Q9NWU1 AK000611 BAA91286 AK225260 AK304821 BAG65569 BC008202 AAH08202 DA916187 JF432169 ADZ15386 XM_006713216 XP_006713279 XM_006713217 XP_006713280 NM_001145391 NP_001138863 NM_017897 NP_060367 NR_026937 |
| Function | May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. {ECO:0000269|PubMed:15668256}. |
| Subcellular Location | Mitochondrion {ECO:0000269|PubMed:15668256}. |
| Tissue Specificity | Widely expressed. Higher expression in heart, skeletal muscle, liver and kidney which contain high levels of active mitochondria. {ECO:0000269|PubMed:15668256}. |
| Top Pathways | Biotin metabolism, Fatty acid biosynthesis, Fatty acid metabolism |