| Gene Symbol |
OXSM
|
| Entrez Gene |
54995
|
| Alt Symbol |
FASN2D, KASI, KS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
3-oxoacyl-ACP synthase, mitochondrial
|
| Other Description |
3-ketoacyl-acyl carrier protein synthase|3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial|3-oxoacyl-acyl-carrier-protein synthase|acyl-malonyl acyl carrier protein-condensing enzyme|beta-ketoacyl synthase|beta-ketoacyl-ACP synthase|type II mitochondrial beta-ketoacyl synthase
|
| Swissprots |
Q9NWU1
|
| Accessions |
CAD22819 CAD22820 CBN69072 CBN70680 EAW64367 EAW64368 EAW64369 Q9NWU1 AK000611 BAA91286 AK225260 AK304821 BAG65569 BC008202 AAH08202 DA916187 JF432169 ADZ15386 XM_006713216 XP_006713279 XM_006713217 XP_006713280 NM_001145391 NP_001138863 NM_017897 NP_060367 NR_026937
|
| Function |
May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. {ECO:0000269|PubMed:15668256}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:15668256}.
|
| Tissue Specificity |
Widely expressed. Higher expression in heart, skeletal muscle, liver and kidney which contain high levels of active mitochondria. {ECO:0000269|PubMed:15668256}.
|
| Top Pathways |
Biotin metabolism, Fatty acid biosynthesis, Fatty acid metabolism
|
![Western Blot: OXSM Overexpression Lysate (Adult Normal) [NBL1-14024] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for OXSM.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4885_OXSM%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14024-img0002.jpg)