Gene Symbol | RNASE2 |
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Entrez Gene | 6036 |
Alt Symbol | EDN, RAF3, RNS2 |
Species | Human |
Gene Type | protein-coding |
Description | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
Other Description | RNase 2|RNase UpI-2|eosinophil-derived neurotoxin|non-secretory ribonuclease|ribonuclease 2|ribonuclease A F3|ribonuclease US |
Swissprots | Q9H2B7 P10153 Q52M39 Q9UCG7 |
Accessions | AAG31577 AAG31578 AAG31579 AAG31580 AAG31581 AAG31582 AAG31583 AAG31584 AAG31585 CAA34546 CAA39459 CAC27640 CDG31919 EAW66435 P10153 BC093678 AAH93678 BC093680 AAH93680 BC096059 AAH96059 M24157 AAA52337 M28129 AAA50284 M30510 AAC82505 X55988 CAA39460 NM_002934 NP_002925 |
Function | This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. {ECO:0000269|PubMed:12578357, ECO:0000269|PubMed:3458170}. |
Subcellular Location | Lysosome {ECO:0000305}. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule. |
Tissue Specificity | Liver, lung, spleen, leukocytes and body fluids. |
Human Eosinophil derived neurotoxin full length protein - ab159356 from Abcam
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Human Eosinophil derived neurotoxin protein fragment - ab159357 from Abcam
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RNASE2 / EDN Antibody Blocking Peptide - LS-E6314 from LifeSpan Bioscience
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Recombinant Human Eosinophil derived neurotoxin Protein - H00006036-Q01 from Novus Biologicals
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Recombinant Human Eosinophil derived neurotoxin Protein - H00006036-P01 from Novus Biologicals
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RNASE2-Antibody-C-term-Blocking-Peptide - BP19003b from Abgent, a WuXi AppTec company
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Recombinant human Non-secretory ribonuclease (OPCA00204) - OPCA00204 from Aviva Systems Biology
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Human RNASE2 protein - orb244496 from Biorbyt
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RNASE2 - H00006036-P01 from Acris Antibodies
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RNASE2 - H00006036-Q01-10 from Acris Antibodies
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RNASE2 - H00006036-Q01-25 from Acris Antibodies
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RNASE2 fusion protein - ag12834 from Proteintech Group
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Recombinant Ribonuclease A2 (RNASE2) - RPD169Hu01 from Uscn Life Science Inc.
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Recombinant Ribonuclease A2 (RNASE2) - RPD169Hu01 from Cloud-clone
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Recombinant Human Non-secretory ribonuclease(RNASE2) - CSB-YP019794HU CSB-BP019794HU CSB-MP019794HU from Cusabio
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Recombinant human Non-secretory ribonuclease - CSB-EP019794HU from Cusabio
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Recombinant Nomascus leucogenys Non-secretory ribonuclease(RNASE2) - CSB-YP844623NHM CSB-EP844623NHM CSB-BP844623NHM CSB-MP844623NHM from Cusabio
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Recombinant Saguinus labiatus Non-secretory ribonuclease(RNASE2) - CSB-YP837335SVY CSB-EP837335SVY CSB-BP837335SVY CSB-MP837335SVY from Cusabio
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Recombinant Callithrix jacchus Non-secretory ribonuclease(RNASE2) - CSB-YP823361CYL CSB-EP823361CYL CSB-BP823361CYL CSB-MP823361CYL from Cusabio
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Recombinant Papio hamadryas Non-secretory ribonuclease(RNASE2) - CSB-YP819363ERJ CSB-EP819363ERJ CSB-BP819363ERJ CSB-MP819363ERJ from Cusabio
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Recombinant Gorilla gorilla gorilla Non-secretory ribonuclease(RNASE2) - CSB-YP019794GGZ CSB-EP019794GGZ CSB-BP019794GGZ CSB-MP019794GGZ from Cusabio
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Recombinant Pan troglodytes Non-secretory ribonuclease(RNASE2) - CSB-YP019794EQV CSB-EP019794EQV CSB-BP019794EQV CSB-MP019794EQV from Cusabio
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Recombinant Pongo pygmaeus Non-secretory ribonuclease(RNASE2) - CSB-YP019794EXP CSB-EP019794EXP CSB-BP019794EXP CSB-MP019794EXP from Cusabio
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Recombinant Saguinus oedipus Non-secretory ribonuclease(RNASE2) - CSB-YP019794SWB CSB-EP019794SWB CSB-BP019794SWB CSB-MP019794SWB from Cusabio
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Non-secretory ribonuclease - RPC140939 from Biomatik
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