| Gene Symbol |
LSM10
|
| Entrez Gene |
84967
|
| Alt Symbol |
MST074, MSTP074
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
LSM10, U7 small nuclear RNA associated
|
| Other Description |
U7 snRNA-associated Sm-like protein LSm10|U7 snRNP-specific Sm-like protein LSM10
|
| Swissprots |
Q969L4
|
| Accessions |
EAX07367 Q969L4 AF166092 AAQ13594 AF394685 AAL07689 AI150247 BC007623 AAH07623 NM_032881 NP_116270
|
| Function |
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. {ECO:0000269|PubMed:16914750}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11574479}.
|
![Western Blot: LSM10 Overexpression Lysate (Adult Normal) [NBL1-12721] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LSM10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/12571_LSM10%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-12721-img0002.jpg)