Gene Symbol | LSM10 |
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Entrez Gene | 84967 |
Alt Symbol | MST074, MSTP074 |
Species | Human |
Gene Type | protein-coding |
Description | LSM10, U7 small nuclear RNA associated |
Other Description | U7 snRNA-associated Sm-like protein LSm10|U7 snRNP-specific Sm-like protein LSM10 |
Swissprots | Q969L4 |
Accessions | EAX07367 Q969L4 AF166092 AAQ13594 AF394685 AAL07689 AI150247 BC007623 AAH07623 NM_032881 NP_116270 |
Function | Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. {ECO:0000269|PubMed:16914750}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11574479}. |
LSM10 CRISPR/Cas9 KO Plasmid (h) - sc-407638 from Santa Cruz Biotechnology
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LSM10 HDR Plasmid (h) - sc-407638-HDR from Santa Cruz Biotechnology
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LSM10 Double Nickase Plasmid (h) - sc-407638-NIC from Santa Cruz Biotechnology
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LSM10 Double Nickase Plasmid (h2) - sc-407638-NIC-2 from Santa Cruz Biotechnology
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LSM10 CRISPR Activation Plasmid (h) - sc-407638-ACT from Santa Cruz Biotechnology
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LSM10 CRISPR Activation Plasmid (h2) - sc-407638-ACT-2 from Santa Cruz Biotechnology
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LSM10 Lentiviral Activation Particles (h) - sc-407638-LAC from Santa Cruz Biotechnology
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LSM10 Lentiviral Activation Particles (h2) - sc-407638-LAC-2 from Santa Cruz Biotechnology
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LSm10 siRNA (h) - sc-75702 from Santa Cruz Biotechnology
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LSm10 shRNA Plasmid (h)-SH - sc-75702-SH from Santa Cruz Biotechnology
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LSm10 shRNA (h) Lentiviral Particles - sc-75702-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU037221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12793 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12793 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03076 from Sigma-Aldrich
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LSM10 siRNA (Human) - CRJ3733 from Cohesion Biosciences
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LSM10 RNAi - H00084967-R01 from Novus Biologicals
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shRNA set against Human LSM10 (NM_032881.1) - SHH335207 from Creative biogene
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shRNA set against Human LSM10(NM_032881.1) - SHH164837 from Creative biogene
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Human LSM10 siRNA - orb274234 from Biorbyt
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LSM10 shRNA Plasmid (Human) - CHJ3733 from Cohesion Biosciences
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LSM10 miRNA 3'UTR clone - MiUTR1H-05939 from Creative biogene
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