Gene Symbol | ACSF3 |
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Entrez Gene | 197322 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA synthetase family member 3 |
Other Description | acyl-CoA synthetase family member 3, mitochondrial|malonyl-CoA synthetase |
Swissprots | C9JQL6 Q4G176 Q8N2F7 Q6INA0 A8K4J8 |
Accessions | CAI72159 CBX47443 EAW66744 Q4G176 AK075499 BAC11654 AK096561 AK290963 BAF83652 BC028399 AAH28399 BC064609 AAH64609 BC072391 AAH72391 BI837487 BM148793 BQ953430 BX325026 BX402632 BX404035 CR976321 DA062861 HY100877 XM_005256293 XP_005256350 XM_011522942 XP_011521244 XM_011522943 XP_011521245 XM_011522944 XP_011521246 XR_933238 XR_933239 XR_933240 XR_933241 NM_001127214 NP_001120686 NM_001243279 NP_001230208 NM_001284316 NP_001271245 NM_174917 NP_777577 NR_045667 NR_104293 NR_045666 |
Function | Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates. {ECO:0000269|PubMed:17762044, ECO:0000269|PubMed:21841779}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:21841779}. |
Top Pathways | Valine, leucine and isoleucine degradation |
ACSF3 CRISPR/Cas9 KO Plasmid (h) - sc-414970 from Santa Cruz Biotechnology
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ACSF3 HDR Plasmid (h) - sc-414970-HDR from Santa Cruz Biotechnology
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ACSF3 Double Nickase Plasmid (h) - sc-414970-NIC from Santa Cruz Biotechnology
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ACSF3 Double Nickase Plasmid (h2) - sc-414970-NIC-2 from Santa Cruz Biotechnology
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ACSF3 CRISPR Activation Plasmid (h) - sc-414970-ACT from Santa Cruz Biotechnology
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ACSF3 CRISPR Activation Plasmid (h2) - sc-414970-ACT-2 from Santa Cruz Biotechnology
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ACSF3 Lentiviral Activation Particles (h) - sc-414970-LAC from Santa Cruz Biotechnology
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ACSF3 Lentiviral Activation Particles (h2) - sc-414970-LAC-2 from Santa Cruz Biotechnology
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ACSF3 siRNA (h) - sc-93074 from Santa Cruz Biotechnology
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ACSF3 shRNA Plasmid (h) - sc-93074-SH from Santa Cruz Biotechnology
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ACSF3 shRNA (h) Lentiviral Particles - sc-93074-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2751 from Sigma-Aldrich
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ACSF3 siRNA (Human) - CRJ6200 from Cohesion Biosciences
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ACSF3 - MBS8211805 from MyBioSource
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shRNA set against Human ACSF3 (NM_174917.3) - SHH230710 from Creative biogene
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Human ACSF3 siRNA - orb276701 from Biorbyt
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ACSF3 shRNA Plasmid (Human) - CHJ6200 from Cohesion Biosciences
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ACSF3 miRNA 3'UTR clone - MiUTR3H-13184 from Creative biogene
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ACSF3 miRNA 3'UTR clone - MiUTR3H-13185 from Creative biogene
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