| Gene Symbol |
ZHX2
|
| Entrez Gene |
22882
|
| Alt Symbol |
AFR1, RAF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc fingers and homeoboxes 2
|
| Other Description |
AFP regulator 1|alpha-fetoprotein regulator 1|regulator of AFP|transcription factor ZHX2|zinc finger and homeodomain protein 2|zinc fingers and homeoboxes protein 2|zinc-fingers and homeoboxes 2
|
| Swissprots |
Q9Y6X8
|
| Accessions |
EAW92012 Q9Y6X8 AB020661 BAA74877 AB083653 BAC76615 AF075099 AI334237 BC042145 AAH42145 BM148156 EU446694 ABZ92223 HG501627 XM_005250836 XP_005250893 XM_005250837 XP_005250894 XM_011516931 XP_011515233 XM_011516932 XP_011515234 NM_014943 NP_055758
|
| Function |
Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. {ECO:0000269|PubMed:12741956}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598}.
|
| Tissue Specificity |
Ubiquitously expressed. Expressed in podocytes. {ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598}.
|
![Western Blot: ZHX2 Overexpression Lysate (Adult Normal) [NBL1-18033] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZHX2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11676_ZHX2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-18033-img0002.jpg)