Gene Symbol | ZHX2 |
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Entrez Gene | 22882 |
Alt Symbol | AFR1, RAF |
Species | Human |
Gene Type | protein-coding |
Description | zinc fingers and homeoboxes 2 |
Other Description | AFP regulator 1|alpha-fetoprotein regulator 1|regulator of AFP|transcription factor ZHX2|zinc finger and homeodomain protein 2|zinc fingers and homeoboxes protein 2|zinc-fingers and homeoboxes 2 |
Swissprots | Q9Y6X8 |
Accessions | EAW92012 Q9Y6X8 AB020661 BAA74877 AB083653 BAC76615 AF075099 AI334237 BC042145 AAH42145 BM148156 EU446694 ABZ92223 HG501627 XM_005250836 XP_005250893 XM_005250837 XP_005250894 XM_011516931 XP_011515233 XM_011516932 XP_011515234 NM_014943 NP_055758 |
Function | Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. {ECO:0000269|PubMed:12741956}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598}. |
Tissue Specificity | Ubiquitously expressed. Expressed in podocytes. {ECO:0000269|PubMed:12741956, ECO:0000269|PubMed:17056598}. |
ZHX2 CRISPR/Cas9 KO Plasmid (h) - sc-407578 from Santa Cruz Biotechnology
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ZHX2 HDR Plasmid (h) - sc-407578-HDR from Santa Cruz Biotechnology
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ZHX2 Double Nickase Plasmid (h) - sc-407578-NIC from Santa Cruz Biotechnology
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ZHX2 Double Nickase Plasmid (h2) - sc-407578-NIC-2 from Santa Cruz Biotechnology
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ZHX2 CRISPR Activation Plasmid (h) - sc-407578-ACT from Santa Cruz Biotechnology
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ZHX2 CRISPR Activation Plasmid (h2) - sc-407578-ACT-2 from Santa Cruz Biotechnology
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ZHX2 Lentiviral Activation Particles (h) - sc-407578-LAC from Santa Cruz Biotechnology
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ZHX2 Lentiviral Activation Particles (h2) - sc-407578-LAC-2 from Santa Cruz Biotechnology
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ZHX2 siRNA (h) - sc-63245 from Santa Cruz Biotechnology
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ZHX2 shRNA Plasmid (h) - sc-63245-SH from Santa Cruz Biotechnology
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ZHX2 shRNA (h) Lentiviral Particles - sc-63245-V from Santa Cruz Biotechnology
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ZHX2 RNAi - H00022882-R01V from Novus Biologicals
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MISSION® esiRNA - EHU039441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23216 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23216 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09030 from Sigma-Aldrich
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ZHX2 siRNA (Human) - CRH7839 from Cohesion Biosciences
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ZHX2 RNAi - H00022882-R01 from Novus Biologicals
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ZHX2 - MBS8206887 from MyBioSource
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shRNA set against Human ZHX2 (NM_014943.3) - SHH452600 from Creative biogene
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shRNA set against Human ZHX2(NM_014943.3) - SHL152976 from Creative biogene
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Human ZHX2 siRNA - orb268341 from Biorbyt
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ZHX2 shRNA Plasmid (Human) - CHH7839 from Cohesion Biosciences
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ZHX2 miRNA 3'UTR clone - MiUTR1H-11450 from Creative biogene
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