Gene Symbol |
EDC4
|
Entrez Gene |
23644
|
Alt Symbol |
GE1, Ge-1, HEDL5, HEDLS, RCD-8, RCD8
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
enhancer of mRNA decapping 4
|
Other Description |
autoantigen Ge-1|autoantigen RCD-8|enhancer of mRNA-decapping protein 4|human enhancer of decapping large subunit
|
Swissprots |
Q6P2E9 Q7Z6H7 Q13826 A6NGM1 Q13025 A8K4T4 Q6ZR12
|
Accessions |
EAW83183 Q6P2E9 AI076562 AI631525 AK128582 AK291049 BAF83738 AK302563 BAH13744 BC043616 AAH43616 BC053598 AAH53598 BC064567 AAH64567 BX445706 DC403765 L26339 AAA21833 U17474 AAB51444 NM_014329 NP_055144
|
Function |
In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). {ECO:0000269|PubMed:16364915}.
|
Subcellular Location |
Cytoplasm, P-body. Nucleus.
|
Top Pathways |
RNA degradation
|