| Gene Symbol |
GCA
|
| Entrez Gene |
25801
|
| Alt Symbol |
GCL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
grancalcin, EF-hand calcium binding protein
|
| Other Description |
grancalcin|grancalcin, EF-hand calcium-binding protein|grancalcin, penta-EF-hand protein
|
| Swissprots |
Q59EP3 Q53TB5 P28676 B2R5X3
|
| Accessions |
AAX93138 EAX11350 EAX11351 P28676 AB209768 BAD93005 AK295413 BAH12058 AK312349 BAG35270 BC005214 AAH05214 BQ005142 HQ448365 ADQ32845 M81637 AAA58498 XM_005246446 XP_005246503 XM_006712398 XP_006712461 XM_006712399 XP_006712462 XM_006712400 XP_006712463 XM_006712401 XP_006712464 XM_011510926 XP_011509228 XM_011510927 XP_011509229 XM_011510928 XP_011509230 NM_012198 NP_036330
|
| Function |
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
|
| Subcellular Location |
Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.
|
| Tissue Specificity |
Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow. {ECO:0000269|PubMed:1737748}.
|
![Western Blot: Grancalcin Overexpression Lysate (Adult Normal) [NBL1-11000] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Grancalcin.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8146_Grancalcin%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11000-img0002.jpg)