Gene Symbol | Abcc1 |
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Entrez Gene | 17250 |
Alt Symbol | Abcc1a, Abcc1b, MRP, Mdrap, Mrp1 |
Species | Mouse |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
Other Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 1a|ATP-binding cassette, sub-family C (CFTR/MRP), member 1b|LTC4 transporter|leukotriene C(4) transporter|multidrug resistance-associated protein 1|multiple drug resistance-associated protein |
Swissprots | O35379 |
Accessions | EDK97393 O35379 AF022908 AAB80938 AF213389 AAF31429 AI853854 AK029876 BAC26654 AK033750 AK045109 BAC32226 AK049174 BAC33586 AK051594 AK140421 AK150015 BAE29240 AK152781 AK162656 BC026509 BC090617 AAH90617 BP762240 XM_006521839 XP_006521902 NM_008576 NP_032602 |
Function | Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. {ECO:0000269|PubMed:9281595}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}. |
Top Pathways | ABC transporters, Vitamin digestion and absorption, MicroRNAs in cancer, Sphingolipid signaling pathway |
MRP1 Polyclonal Antibody - bs-0657R from Bioss
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MRP1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0657R-A350 from Bioss
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MRP1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0657R-A488 from Bioss
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MRP1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0657R-A555 from Bioss
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MRP1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0657R-A647 from Bioss
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MRP1 Polyclonal Antibody, Cy3 Conjugated - bs-0657R-Cy3 from Bioss
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MRP1 Polyclonal Antibody, Cy5 Conjugated - bs-0657R-Cy5 from Bioss
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MRP1 Polyclonal Antibody, Cy5.5 Conjugated - bs-0657R-Cy5.5 from Bioss
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MRP1 Polyclonal Antibody, Cy7 Conjugated - bs-0657R-Cy7 from Bioss
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MRP1 Polyclonal Antibody, FITC Conjugated - bs-0657R-FITC from Bioss
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MRP1 Polyclonal Antibody, Biotin Conjugated - bs-0657R-Biotin from Bioss
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MRP1 Polyclonal Antibody, HRP Conjugated - bs-0657R-HRP from Bioss
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ABCC1 Antibody (OABF00243) - OABF00243 from Aviva Systems Biology
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MRP antibody - 10R-2353 from Fitzgerald
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MRP1 Antibody - abx104170 from Abbexa
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MRP1 Antibody - abx104504 from Abbexa
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Anti-ABCC1 antibody - STJ71643 from St John's Laboratory Ltd
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MRP, Monoclonal Antibody - MBS831071 from MyBioSource
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Polyclonal Antibody to Multidrug Resistance Associated Protein 1 (MRP1) - PAB068Mu01 from Cloud-clone
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Rabbit-Anti-MRP1-Polyclonal-Antibody - AP52039 from Abgent, a WuXi AppTec company
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MRP1, Polyclonal Antibody - MBS9216286 from MyBioSource
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MRP1 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated - bs-0657R-A594 from Bioss
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anti-MRP1 antibody - ARG10603 from Arigo Biolaboratories |
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MRP1 Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated - bs-0657R-A680 from Bioss
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MRP1 Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated - bs-0657R-A750 from Bioss
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