Gene Symbol |
DPY19L2
|
Entrez Gene |
283417
|
Alt Symbol |
SPATA34, SPGF9
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
dpy-19-like 2 (C. elegans)
|
Other Description |
probable C-mannosyltransferase DPY19L2|protein dpy-19 homolog 2|spermatogenesis associated 34
|
Swissprots |
Q6UWG8 Q6NUT2 B4E191 A4FVC1 Q96LZ9 Q3ZCX2
|
Accessions |
EAW97117 EAW97118 Q6NUT2 AK057511 BAB71515 AK303727 BAG64703 AK310102 AL833344 AY358792 AAQ89152 BC031225 AAH31225 BC068442 AAH68442 BC125215 AAI25216 BC125216 AAI25217 DB514316 XM_006719348 XP_006719411 XM_006719350 XP_006719413 XM_006719352 XP_006719415 XM_006719353 XP_006719416 XM_006719355 XP_006719418 XM_006719356 XP_006719419 XM_011538215 XP_011536517 XM_011538216 XP_011536518 XM_011538217 XP_011536519 XM_011538218 XP_011536520 XR_429092 XR_944521 NM_173812 NP_776173
|
Function |
Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation. {ECO:0000250, ECO:0000269|PubMed:21397063, ECO:0000269|PubMed:21397064}.
|
Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
Tissue Specificity |
Widely expressed with high expression in testis. Not detectable in ejaculated sperm (at protein level). {ECO:0000269|PubMed:16526957, ECO:0000269|PubMed:21397064}.
|