Gene Symbol | DPY19L2 |
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Entrez Gene | 283417 |
Alt Symbol | SPATA34, SPGF9 |
Species | Human |
Gene Type | protein-coding |
Description | dpy-19-like 2 (C. elegans) |
Other Description | probable C-mannosyltransferase DPY19L2|protein dpy-19 homolog 2|spermatogenesis associated 34 |
Swissprots | Q6UWG8 Q6NUT2 B4E191 A4FVC1 Q96LZ9 Q3ZCX2 |
Accessions | EAW97117 EAW97118 Q6NUT2 AK057511 BAB71515 AK303727 BAG64703 AK310102 AL833344 AY358792 AAQ89152 BC031225 AAH31225 BC068442 AAH68442 BC125215 AAI25216 BC125216 AAI25217 DB514316 XM_006719348 XP_006719411 XM_006719350 XP_006719413 XM_006719352 XP_006719415 XM_006719353 XP_006719416 XM_006719355 XP_006719418 XM_006719356 XP_006719419 XM_011538215 XP_011536517 XM_011538216 XP_011536518 XM_011538217 XP_011536519 XM_011538218 XP_011536520 XR_429092 XR_944521 NM_173812 NP_776173 |
Function | Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation. {ECO:0000250, ECO:0000269|PubMed:21397063, ECO:0000269|PubMed:21397064}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed with high expression in testis. Not detectable in ejaculated sperm (at protein level). {ECO:0000269|PubMed:16526957, ECO:0000269|PubMed:21397064}. |
DPY19L2 CRISPR/Cas9 KO Plasmid (h) - sc-410406 from Santa Cruz Biotechnology
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DPY19L2 HDR Plasmid (h) - sc-410406-HDR from Santa Cruz Biotechnology
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DPY19L2 Double Nickase Plasmid (h) - sc-410406-NIC from Santa Cruz Biotechnology
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DPY19L2 Double Nickase Plasmid (h2) - sc-410406-NIC-2 from Santa Cruz Biotechnology
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DPY19L2 CRISPR Activation Plasmid (h) - sc-410406-ACT from Santa Cruz Biotechnology
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DPY19L2 CRISPR Activation Plasmid (h2) - sc-410406-ACT-2 from Santa Cruz Biotechnology
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DPY19L2 Lentiviral Activation Particles (h) - sc-410406-LAC from Santa Cruz Biotechnology
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DPY19L2 Lentiviral Activation Particles (h2) - sc-410406-LAC-2 from Santa Cruz Biotechnology
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DPY19L2 siRNA (h) - sc-95801 from Santa Cruz Biotechnology
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DPY19L2 shRNA Plasmid (h) - sc-95801-SH from Santa Cruz Biotechnology
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DPY19L2 shRNA (h) Lentiviral Particles - sc-95801-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU112901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7473 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7473 from Sigma-Aldrich
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DPY19L2 siRNA (Human) - CRJ6903 from Cohesion Biosciences
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DPY19L2 - MBS8205965 from MyBioSource
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shRNA set against Human DPY19L2 (NM_173812.4) - SHH280813 from Creative biogene
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Human DPY19L2 siRNA - orb277404 from Biorbyt
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DPY19L2 shRNA Plasmid (Human) - CHJ6903 from Cohesion Biosciences
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DPY19L2 miRNA 3'UTR clone - MiUTR1H-02985 from Creative biogene
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