Gene Symbol |
INTS2
|
Entrez Gene |
57508
|
Alt Symbol |
INT2, KIAA1287
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
integrator complex subunit 2
|
Other Description |
-
|
Swissprots |
Q9ULD3 Q9H0H0
|
Accessions |
EAW51434 EAW51435 EAW51436 Q9H0H0 AB033113 BAA86601 AK299032 BAG61107 AK308307 AL136800 CAB66734 AM393379 CAL38257 BK005721 DAA05721 CR533582 CAG38656 XM_005257537 XP_005257594 XM_006721987 XP_006722050 XM_011525058 XP_011523360 XR_934509 NM_020748 NP_065799 NR_026641
|
Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
|
Subcellular Location |
Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|