Gene Symbol | INTS2 |
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Entrez Gene | 57508 |
Alt Symbol | INT2, KIAA1287 |
Species | Human |
Gene Type | protein-coding |
Description | integrator complex subunit 2 |
Other Description | - |
Swissprots | Q9ULD3 Q9H0H0 |
Accessions | EAW51434 EAW51435 EAW51436 Q9H0H0 AB033113 BAA86601 AK299032 BAG61107 AK308307 AL136800 CAB66734 AM393379 CAL38257 BK005721 DAA05721 CR533582 CAG38656 XM_005257537 XP_005257594 XM_006721987 XP_006722050 XM_011525058 XP_011523360 XR_934509 NM_020748 NP_065799 NR_026641 |
Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
Subcellular Location | Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
INTS2 CRISPR/Cas9 KO Plasmid (h) - sc-412818 from Santa Cruz Biotechnology
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INTS2 HDR Plasmid (h) - sc-412818-HDR from Santa Cruz Biotechnology
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INTS2 Double Nickase Plasmid (h) - sc-412818-NIC from Santa Cruz Biotechnology
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INTS2 Double Nickase Plasmid (h2) - sc-412818-NIC-2 from Santa Cruz Biotechnology
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INTS2 CRISPR Activation Plasmid (h) - sc-412818-ACT from Santa Cruz Biotechnology
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INTS2 CRISPR Activation Plasmid (h2) - sc-412818-ACT-2 from Santa Cruz Biotechnology
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INTS2 Lentiviral Activation Particles (h) - sc-412818-LAC from Santa Cruz Biotechnology
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INTS2 Lentiviral Activation Particles (h2) - sc-412818-LAC-2 from Santa Cruz Biotechnology
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INTS2 siRNA (h) - sc-93707 from Santa Cruz Biotechnology
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INTS2 shRNA Plasmid (h) - sc-93707-SH from Santa Cruz Biotechnology
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INTS2 shRNA (h) Lentiviral Particles - sc-93707-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU135211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10712 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10712 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11238 from Sigma-Aldrich
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INTS2 siRNA (Human) - CRJ1494 from Cohesion Biosciences
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INTS2 - MBS8214673 from MyBioSource
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shRNA set against Human Ints2 (NM_020748.2) - SHH319965 from Creative biogene
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Human INTS2 siRNA - orb271995 from Biorbyt
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INTS2 shRNA Plasmid (Human) - CHJ1494 from Cohesion Biosciences
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INTS2 miRNA 3'UTR clone - MiUTR4H-TG04542 from Creative biogene
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