CPN1

Gene Symbol	CPN1
Entrez Gene	1369
Alt Symbol	CPN, SCPN
Species	Human
Gene Type	protein-coding
Description	carboxypeptidase N, polypeptide 1
Other Description	anaphylatoxin inactivator\|arginine carboxypeptidase\|carboxypeptidase K\|carboxypeptidase N catalytic chain\|carboxypeptidase N catalytic subunit\|carboxypeptidase N polypeptide 1 50 kD\|carboxypeptidase N small subunit\|kininase I\|kininase-1\|lysine carboxypeptidase\|plasma carboxypeptidase B\|serum carboxypeptidase N
Swissprots	B1AP59 P15169
Accessions	EAW49848 P15169 AK313972 BAG36687 AW950687 BC027897 AAH27897 DQ892051 ABM82977 DQ895244 ABM86170 DQ895245 ABM86171 X14329 CAA32507 XM_011539299 XP_011537601 NM_001308 NP_001299
Function	Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Subcellular Location	Secreted, extracellular space.
Tissue Specificity	Synthesized in the liver and secreted in plasma.

CPN cat (C-20) - sc-18966 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Cat
Clonality	Polyclonal

CPN cat (C-20): sc-18966. Western blot analysis of CPN cat expression in Hep G2 whole cell lysate.

Anti-CPN1 antibody - ab171323 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram). An FITC-conjugated goat-anti-rabbit secondary antibody was used for the analysis.

Anti-CPN1 antibody - ab86556 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 antibody (ab86556) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CPN1 antibody - ab74243 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-CPN1 antibody (ab74243) at 1/500 dilutionLane 1 : Extracts from RAW264.7 cellsLane 2 : Extracts from RAW264.7 cells plus 5µg immunizing peptideLysates/proteins at 5 µg per lane.

Anti-CPN1 antibody [EPR6229] - ab124874 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6229

All lanes : Anti-CPN1 antibody [EPR6229] (ab124874) at 1/1000 dilutionLane 1 : Human plasma lysateLane 2 : HepG2 lysateLane 3 : Human fetal liver lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CPN1 / ACBP Antibody (Internal, clone EPR6229) IHC-plus™ - LS-B6751 from LifeSpan Bioscience

Host	Rabbit
Clonality	Monoclonal
Clone	[EPR6229]

Anti-CPN1 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6751 dilution 1:50.

Anti-CPN1 / ACBP Antibody (aa323-372) - LS-C111346 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

CPN1 antibody LS-C111346 Western blot of Transfected 293T cell lysate.

Anti-CPN1 / ACBP Antibody (aa159-325) - LS-C293185 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (aa409-458) - LS-C119821 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Western blot of extracts from RAW264.7 cells, using CPN1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CPN1 / ACBP Antibody (Gln452) - LS-C177445 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Western blot of CPN antibody in extracts from RAW264.7 cells.

Anti-CPN1 / ACBP Antibody (aa221-449, Biotin) - LS-C297353 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (aa159-325) - LS-C293164 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Western blot of recombinant CPN1 / ACBP.

Anti-CPN1 / ACBP Antibody (aa159-325, Biotin) - LS-C299997 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (aa159-325, Biotin) - LS-C298048 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (aa159-325, FITC) - LS-C301825 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (aa221-449) - LS-C293167 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (N-Terminus) - LS-C100516 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Western blot of CPN1 (arrow) using rabbit polyclonal CPN1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CPN1 gene.

Anti-CPN1 / ACBP Antibody (aa159-325, FITC) - LS-C304170 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (aa221-449, FITC) - LS-C304802 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 / ACBP Antibody (Met25) - LS-C177244 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

IHC of ACBP (M25) pAb in paraffin-embedded human liver carcinoma tissue.

Anti-CPN1 / ACBP Antibody (aa209-240) - LS-C166993 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

CPN1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CPN1 / ACBP Antibody (aa251-300) IHC-plus™ - LS-B5828 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5828 concentration 2.5 ug/ml.

CPN1 Antibody - NBP1-57960 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

CPN1 Antibody - NBP1-58016 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CPN1 antibody produced in rabbit - HPA040323 from Sigma-Aldrich

Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-CPN1: <B>Cat. No. HPA040323</B>: Immunohistochemical staining of human liver shows moderate cytoplasmic positivity in hepatocytes.

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