Gene Symbol |
PAPD4
|
Entrez Gene |
167153
|
Alt Symbol |
GLD2, TUT2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
PAP associated domain containing 4
|
Other Description |
PAP-associated domain-containing protein 4|TUTase 2|hGLD-2|poly(A) RNA polymerase GLD2|terminal uridylyltransferase 2
|
Swissprots |
Q6PIY7 Q8N927 Q86WZ2
|
Accessions |
EAW95837 EAW95838 Q6PIY7 AK095818 BAC04629 AL833136 BC026061 AAH26061 BC047581 AAH47581 CN348312 DB142133 XM_006714563 XP_006714626 XM_011543219 XP_011541521 XM_011543220 XP_011541522 XM_011543221 XP_011541523 XM_011543222 XP_011541524 XM_011543223 XP_011541525 XM_011543224 XP_011541526 XM_011543225 XP_011541527 XM_011543226 XP_011541528 XM_011543227 XP_011541529 XM_011543228 XP_011541530 XM_011543229 XP_011541531 XM_011543230 XP_011541532 XM_011543231 XP_011541533 XM_011543232 XP_011541534 XM_011543233 XP_011541535 XR_948240 NM_001114393 NP_001107865 NM_001114394 NP_001107866 NM_001297744 NP_001284673 NM_001297745 NP_001284674 NM_173797 NP_776158
|
Function |
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
Tissue Specificity |
Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla. {ECO:0000269|PubMed:15987818}.
|