Gene Symbol | PAPD4 |
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Entrez Gene | 167153 |
Alt Symbol | GLD2, TUT2 |
Species | Human |
Gene Type | protein-coding |
Description | PAP associated domain containing 4 |
Other Description | PAP-associated domain-containing protein 4|TUTase 2|hGLD-2|poly(A) RNA polymerase GLD2|terminal uridylyltransferase 2 |
Swissprots | Q6PIY7 Q8N927 Q86WZ2 |
Accessions | EAW95837 EAW95838 Q6PIY7 AK095818 BAC04629 AL833136 BC026061 AAH26061 BC047581 AAH47581 CN348312 DB142133 XM_006714563 XP_006714626 XM_011543219 XP_011541521 XM_011543220 XP_011541522 XM_011543221 XP_011541523 XM_011543222 XP_011541524 XM_011543223 XP_011541525 XM_011543224 XP_011541526 XM_011543225 XP_011541527 XM_011543226 XP_011541528 XM_011543227 XP_011541529 XM_011543228 XP_011541530 XM_011543229 XP_011541531 XM_011543230 XP_011541532 XM_011543231 XP_011541533 XM_011543232 XP_011541534 XM_011543233 XP_011541535 XR_948240 NM_001114393 NP_001107865 NM_001114394 NP_001107866 NM_001297744 NP_001284673 NM_001297745 NP_001284674 NM_173797 NP_776158 |
Function | Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla. {ECO:0000269|PubMed:15987818}. |
PAPD4 CRISPR/Cas9 KO Plasmid (h) - sc-406948 from Santa Cruz Biotechnology
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PAPD4 HDR Plasmid (h) - sc-406948-HDR from Santa Cruz Biotechnology
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PAPD4 Double Nickase Plasmid (h) - sc-406948-NIC from Santa Cruz Biotechnology
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PAPD4 Double Nickase Plasmid (h2) - sc-406948-NIC-2 from Santa Cruz Biotechnology
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PAPD4 CRISPR Activation Plasmid (h) - sc-406948-ACT from Santa Cruz Biotechnology
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PAPD4 CRISPR Activation Plasmid (h2) - sc-406948-ACT-2 from Santa Cruz Biotechnology
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PAPD4 Lentiviral Activation Particles (h) - sc-406948-LAC from Santa Cruz Biotechnology
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PAPD4 Lentiviral Activation Particles (h2) - sc-406948-LAC-2 from Santa Cruz Biotechnology
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PAPD4 siRNA (h) - sc-91706 from Santa Cruz Biotechnology
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PAPD4 shRNA Plasmid (h) - sc-91706-SH from Santa Cruz Biotechnology
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PAPD4 shRNA (h) Lentiviral Particles - sc-91706-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU026381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16311 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07657 from Sigma-Aldrich
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PAPD4 siRNA (Human) - CRJ6055 from Cohesion Biosciences
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PAPD4 RNAi - H00167153-R01 from Novus Biologicals
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shRNA set against Human PAPD4 (NM_173797.3) - SHH370448 from Creative biogene
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shRNA set against Human PAPD4(NM_173797.3) - SHR087324 from Creative biogene
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Human PAPD4 siRNA - orb276556 from Biorbyt
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PAPD4 shRNA Plasmid (Human) - CHJ6055 from Cohesion Biosciences
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PAPD4 miRNA 3'UTR clone - MiUTR1H-07494 from Creative biogene
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PAPD4 miRNA 3'UTR clone - MiUTR3H-13137 from Creative biogene
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PAPD4 miRNA 3'UTR clone - MiUTR3H-13138 from Creative biogene
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