| Gene Symbol |
KRT73
|
| Entrez Gene |
319101
|
| Alt Symbol |
IRT6IRS3, K6IRS3, KRT6IRS3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
keratin 73, type II
|
| Other Description |
CK-73|K73|cytokeratin-73|keratin 6 irs3|keratin, type II cytoskeletal 73|keratin-73|type II inner root sheath-specific keratin-K6irs3|type-II keratin Kb36
|
| Swissprots |
Q32MB2 Q86Y46
|
| Accessions |
EAW96640 Q86Y46 AJ508776 CAD48513 BC109212 AAI09213 XM_011538257 XP_011536559 XM_011538258 XP_011536560 NM_175068 NP_778238
|
| Function |
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation. Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level). {ECO:0000269|PubMed:12648212, ECO:0000269|PubMed:16874310}.
|
![Western Blot: KRT73 Overexpression Lysate (Adult Normal) [NBP2-05076] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KRT73.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7174_KRT73%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05076-img0001.jpg)